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Fig. 2 | Cardiovascular Diabetology

Fig. 2

From: MCT4-dependent lactate transport: a novel mechanism for cardiac energy metabolism injury and inflammation in type 2 diabetes mellitus

Fig. 2

A Representative diagram and quantification of ROS using DCFH-DA staining in H9C2 cells treated with palmitic acid (PA). B Representative diagram and quantification of ROS in PMCM cells treated with PA. C Quantification of Λψm (mitochondrial membrane potential) in H9C2 cells treated with PA. D Fold change of lactic acid in H9C2 whole cell lysates after time-dependent PA stimulation. E Fold change of lactic acid in H9C2 cell supernatant after time-dependent PA stimulation. F Mct4 mRNA expression in H9C2 cells treated with PA. G Western blot analysis and quantification of MCT4 in H9C2 cells treated with PA. H Fold change in whole-cell abundances of lactic acid in H9C2 treated with PA and/or VB124. I Fold change in cell supernatant abundances of lactic acid in H9C2 treated with PA and/or VB124. J Representative diagram and quantification of ROS in PMCM and H9C2 cells treated with PA and/or VB124. K Representative diagram and quantification of Λψm in H9C2 cells treated with PA and/or VB124. L Fold change of ATP content in H9C2 treated with PA and/or VB124

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