Fig. 5
From: The SGLT2 inhibitor Empagliflozin promotes post-stroke functional recovery in diabetic mice
Effect of Empagliflozin on neuroinflammation after stroke. Iba-1 expression in striatum of non-diabetic controls (non-T2D), diabetic mice (T2D-VH) and diabetic mice treated with Empagliflozin (T2D-E) after stroke. Data are presented as mean ± SD. Statistical significance was calculated using two-way ANOVA followed by Benjamini, Krieger and Yekutieli multiple comparisons test. Results were considered statistically significant if p < 0.05. *denotes a significant difference between non-T2D and T2D-VH in the same hemisphere, #denotes a significant difference between the contralateral and ipsilateral hemisphere within the same group. # and *denote p < 0.05, ###denotes p < 0.001 and ####denotes p < 0.0001. non-T2D n = 6, T2D-VH n = 9, T2D-E n = 9