Table 5 Segmented Cox regression analysis and trend test of HOMA-IR

HOMA-IR < 3.59

 HOMA-IR dichotomous

  Low

Reference

Reference

Reference

  High

0.81 (0.63, 1.02) 0.0751

0.69 (0.54, 0.87) 0.0023

0.96 (0.73, 1.26) 0.7673

HOMA-IR quartile

  Q1

Reference

Reference

Reference

  Q2

0.68 (0.49, 0.94) 0.0193

0.69 (0.49, 0.96) 0.0275

0.68 (0.47, 0.99) 0.0460

  Q3

0.67 (0.48, 0.93) 0.0159

0.59 (0.43, 0.83) 0.0020

0.82 (0.56, 1.20) 0.3153

  Q4

0.65 (0.47, 0.91) 0.0127

0.54 (0.39, 0.76) 0.0004

0.73 (0.49, 1.07) 0.1042

  P trend

0.0185

0.0004

0.2615

HOMA-IR > 3.59

 HOMA-IR dichotomous

  Low

Reference

Reference

Reference

  High

1.11 (0.83, 1.49) 0.4635

1.44 (1.07, 1.95) 0.0166

1.16 (0.84, 1.60) 0.3774

 HOMA-IR quartile

  Q1

Reference

Reference

Reference

  Q2

0.95 (0.62, 1.44) 0.8005

0.93 (0.61, 1.43) 0.7427

0.93 (0.59, 1.45) 0.7436

  Q3

1.03 (0.68, 1.56) 0.8769

1.37 (0.90, 2.10) 0.1411

1.00 (0.63, 1.60) 0.9870

  Q4

1.14 (0.75, 1.73) 0.5312

1.41 (0.92, 2.15) 0.1122

1.22 (0.78, 1.91) 0.3784

  P trend

0.3996

0.0618

0.6046