Table 3 Survival analysis and incidence analysis of major CV and coronary events by Cox proportional hazards regression according to FLI categories at baseline independently of ST1-RE (model 1) or ST1-RE and prior CV events (model 2)
| Â | Model 1 | Model 2 | ||||
|---|---|---|---|---|---|---|
| Â | HR | 95% CI | p | HR | 95% CI | p |
All-cause mortality | ||||||
FLI categories | Â | Â | 0.003 | Â | Â | 0.004 |
 FLI < 30 | 1 |  |  | 1 |  |  |
 FLI 30–59 | 1.52 | 0.78–2.97 | 0.222 | 1.48 | 0.75–2.90 | 0.256 |
 FLI ≥ 60 | 3.04 | 1.59–5.82 | 0.001 | 2.95 | 1.54–5.67 | 0.001 |
ST1-RE categories |  |  |  < 0.0001 |  |  |  < 0.0001 |
 10-year risk < 10% | 1 |  |  | 1 |  |  |
 10-year risk 10–19% | 3.51 | 1.43–8.64 | 0.006 | 3.46 | 1.41–8.52 | 0.007 |
 10-year risk ≥ 20% | 14.09 | 6.38–31.10 |  < 0.0001 | 13.00 | 5.81–29.10 |  < 0.0001 |
Prior CV events | – | 1.56 | 0.78–3.10 | 0.209 | ||
Major CV events | ||||||
FLI categories | Â | Â | 0.012 | Â | Â | 0.042 |
 FLI < 30 | 1 |  |  | 1 |  |  |
 FLI 30–59 | 1.80 | 0.90–3.61 | 0.096 | 1.53 | 0.78–3.16 | 0.204 |
 FLI ≥ 60 | 2.98 | 1.45–6.13 | 0.003 | 2.55 | 1.23–5.27 | 0.012 |
ST1-RE categories |  |  |  < 0.0001 |  |  |  < 0.0001 |
 10-year risk < 10% | 1 |  |  | 1 |  |  |
 10-year risk 10–19% | 3.50 | 1.44–8.52 | 0.006 | 3.19 | 1.31–7.77 | 0.011 |
 10-year risk ≥ 20% | 10.77 | 4.76–24.40 |  < 0.0001 | 7.36 | 3.15–17.20 |  < 0.0001 |
Prior CV events | – | 5.51 | 2.88–10.55 |  < 0.0001 | ||
Coronary events | ||||||
FLI categories | Â | Â | 0.031 | Â | Â | 0.073 |
 FLI < 30 | 1 |  |  | 1 |  |  |
 FLI 30–59 | 1.63 | 0.71–3.75 | 0.247 | 1.34 | 0.58–3.12 | 0.495 |
 FLI ≥ 60 | 3.07 | 1.33–7.08 | 0.009 | 2.62 | 1.12–6.10 | 0.026 |
ST1-RE categories |  |  |  < 0.0001 |  |  | 0.004 |
 10-year risk < 10% | 1 |  |  | 1 |  |  |
 10-year risk 10–19% | 3.14 | 1.19–8.33 | 0.021 | 2.88 | 1.08–7.66 | 0.034 |
 10-year risk ≥ 20% | 7.86 | 3.16–19.56 |  < 0.0001 | 5.09 | 1.94–13.33 | 0.001 |
Prior CV events | – | 5.84 | 2.63–12.94 |  < 0.0001 | ||