Table 1 The baseline characteristics of participants
TyG-BMI quartile | Q1 (< 175.14) | Q2 (175.14–198.79) | Q3 (198.79–228.35) | Q4 (≥ 228.35) | P-value |
|---|---|---|---|---|---|
Participants (n) | 2175 | 2174 | 2174 | 2175 | Â |
Age (years, mean ± SD) | 61.9 ± 9.9 | 59.4 ± 9.2 | 58.7 ± 8.9 | 57.5 ± 8.5 | < 0.001 |
PLT (109/L, mean ± SD) | 208.41 ± 76.22 | 210.43 ± 72.23 | 209.89 ± 70.63 | 217.45 ± 71.30 | < 0.001 |
WBC (109/L, mean ± SD) | 6.05 ± 1.98 | 6.15 ± 1.85 | 6.21 ± 1.78 | 6.55 ± 1.90 | < 0.001 |
BUN (mg/L, mean ± SD) | 45.60 ± 14.04 | 44.44 ± 13.02 | 43.21 ± 11.76 | 42.99 ± 11.95 | < 0.001 |
FPG (mg/L, mean ± SD) | 99.17 ± 18.79 | 104.95 ± 26.84 | 109.82 ± 32.37 | 125.99 ± 52.62 | < 0.001 |
Scr (mg/dL, mean ± SD) | 0.78 ± 0.24 | 0.78 ± 0.30 | 0.78 ± 0.18 | 0.78 ± 0.20 | 0.707 |
eGFR (mL/min·1.73 m2, mean ± SD) | 96.54 ± 15.47 | 97.29 ± 15.28 | 96.84 ± 15.58 | 96.72 ± 15.99 | 0.433 |
TC (mg/dL, mean ± SD) | 183.83 ± 35.25 | 190.64 ± 37.15 | 196.32 ± 37.42 | 203.63 ± 40.65 | < 0.001 |
TG (mg/dL,median, quartile) | 73.46 (57.53–94.69) | 92.93 (71.02–124.79) | 116.82 (87.61–161.96) | 165.49 (120.36–243.38) | < 0.001 |
TyG(mean ± SD) | 8.20 ± 0.44 | 8.49 ± 0.46 | 8.77 ± 0.52 | 9.26 ± 0.68 | < 0.001 |
TyG-BMI (mean ± SD) | 158.34 ± 12.84 | 186.80 ± 6.86 | 212.56 ± 8.35 | 256.36 ± 22.38 | < 0.001 |
HDL-c (mg/dL, mean ± SD) | 59.89 ± 15.79 | 54.75 ± 14.38 | 49.01 ± 13.04 | 42.16 ± 11.58 | < 0.001 |
LDL-c (mg/Dl, mean ± SD) | 109.75 ± 30.75 | 116.90 ± 32.86 | 120.86 ± 34.12 | 119.07 ± 40.05 | < 0.001 |
CRP (mg/L median, quartile) | 0.77 (0.44–1.81) | 0.83 (0.48–1.80) | 1.05 (0.58–2.07) | 1.43 (0.80–2.73) | < 0.001 |
HBA1C (%, mean ± SD) | 5.09 ± 0.52 | 5.18 ± 0.68 | 5.23 ± 0.70 | 5.56 ± 1.10 | < 0.001 |
UA (mg/dL, mean ± SD) | 4.29 ± 1.21 | 4.31 ± 1.19 | 4.49 ± 1.27 | 4.66 ± 1.27 | < 0.001 |
HGB (g/L, mean ± SD) | 13.96 ± 2.23 | 14.26 ± 2.26 | 14.31 ± 2.06 | 14.67 ± 2.28 | < 0.001 |
SBP (mmHg, mean ± SD) | 124.88 ± 21.75 | 126.96 ± 20.48 | 130.60 ± 21.21 | 134.43 ± 21.47 | < 0.001 |
DBP (mmHg, mean ± SD) | 71.81 ± 11.75 | 73.99 ± 11.72 | 76.57 ± 11.75 | 79.51 ± 12.29 | < 0.001 |
Cystatin C (mg/L, mean ± SD) | 1.06 ± 0.27 | 1.02 ± 0.32 | 0.99 ± 0.24 | 0.96 ± 0.25 | < 0.001 |
BMI (kg/m2, mean ± SD) | 19.36 ± 1.70 | 22.07 ± 1.34 | 24.30 ± 1.54 | 27.77 ± 2.51 | < 0.001 |
Sex (N, %) | < 0.001 | ||||
 Male | 1240 (57.01%) | 1064 (48.94%) | 912 (41.95%) | 791 (36.37%) |  |
 Female | 935 (42.99%) | 1110 (51.06%) | 1262 (58.05%) | 1384 (63.63%) |  |
Hypertension (N, %) | 272 (12.51%) | 362 (16.65%) | 550 (25.30%) | 872 (40.09%) | < 0.001 |
DM (N, %) | 38 (1.75%) | 68 (3.13%) | 121 (5.57%) | 247 (11.36%) | < 0.001 |
Malignant tumors (N, %) | 25 (1.15%) | 15 (0.69%) | 18 (0.83%) | 32 (1.47%) | 0.051 |
CLD (N, %) | 318 (14.62%) | 220 (10.12%) | 185 (8.51%) | 194 (8.92%) | < 0.001 |
CKD (N, %) | 170 (7.82%) | 144 (6.62%) | 139 (6.39%) | 125 (5.75%) | 0.049 |
Smoking status (N, %) | < 0.001 | ||||
 Never | 1087 (49.98%) | 1276 (58.69%) | 1435 (66.01%) | 1524 (70.07%) |  |
 Ever | 171 (7.86%) | 167 (7.68%) | 197 (9.06%) | 208 (9.56%) |  |
 Current | 917 (42.16%) | 731 (33.62%) | 542 (24.93%) | 443 (20.37%) |  |
Drinking status (N, %) | < 0.001 | ||||
 Never | 311 (14.30%) | 296 (13.62%) | 300 (13.80%) | 281 (12.92%) |  |
 Ever | 1226 (56.37%) | 1281 (58.92%) | 1357 (62.42%) | 1463 (67.26%) |  |
 Current | 638 (29.33%) | 597 (27.46%) | 517 (23.78%) | 431 (19.82%) |  |