Table 1 Demographic and clinical characteristics of the study population according to the AIP
|  | Low tertile (n = 3741) | Middle tertile (n = 3740) | High tertile (n = 3740) | P value |
|---|---|---|---|---|
Sociodemographic characteristics |  |  |  |  |
 Age (years) | 66 ± 11 | 63 ± 11 | 59 ± 12 | < 0.001 |
 Male sex | 2748 (73.5%) | 2822 (75.5%) | 2971 (79.4%) | < 0.001 |
 BMI | 23.8 ± 3.3 | 24.8 ± 3.3 | 25.4 ± 3.4 | < 0.001 |
 Smokes | 1690 (45.2%) | 1821 (48.7%) | 2017 (53.9%) | < 0.001 |
 Drinks alcohol | 706 (18.9%) | 733 (19.6%) | 829 (22.2%) | < 0.001 |
Medical history | Â | Â | Â | Â |
 Hypertension | 1959 (52.4%) | 2080 (55.6%) | 2159 (57.7%) | < 0.001 |
 Dyslipidemia | 307 (8.2%) | 423 (11.3%) | 520 (13.9%) | < 0.001 |
 DM | 874 (23.3%) | 1127 (30.1%) | 1314 (35.1%) | < 0.001 |
 Hypoglycemia intervention | 765(26.8%) | 971(34.0%) | 1117 (39.1%) | < 0.001 |
 Angina | 971 (26.0%) | 935 (25.0%) | 978 (26.1%) | 0.476 |
 Myocardial infarction | 335 (9.0%) | 339 (9.1%) | 362 (9.7%) | 0.506 |
 PCI | 438 (11.7%) | 440 (11.8%) | 437 (11.7%) | 0.994 |
 TIA | 289 (7.7%) | 285 (7.6%) | 220 (5.9%) | 0.002 |
Body mass index status |  |  |  |  |
 Underweight | 160 (4.3%) | 59 (1.6%) | 58 (1.6%) | < 0.001 |
 Healthy weight | 1819 (48.6%) | 1432 (38.3%) | 1177 (31.5%) | < 0.001 |
 Overweight | 1437 (38.4%) | 1704 (45.6%) | 1772 (47.4%) | < 0.001 |
 Obese | 325 (8.7%) | 545 (14.6%) | 733 (19.6%) | < 0.001 |
Laboratory tests | Â | Â | Â | Â |
 FBG (mmol/L) | 5.8 (5.0–7.4) | 6.0 (5.1–7.8) | 6.4 (5.2–8.5) | < 0.001 |
 HbA1c (%) | 5.9 (5.5–6.6) | 6.1 (5.6–7.2) | 6.4 (5.7–7.8) | < 0.001 |
 TC (mmol/L) | 4.3 ± 1.1 | 4.4 ± 1.2 | 4.6 ± 1.4 | < 0.001 |
 LDL-C (mmol/L) | 2.6 ± 1.0 | 2.8 ± 1.0 | 2.8 ± 1.0 | < 0.001 |
 TG (mmol/L) | 0.9 (0.7–1.1) | 1.5 (1.3–1.8) | 2.7 (2.1–3.6) | < 0.001 |
 HDL-C (mmol/L) | 1.2 (1.1–1.4) | 1.0 (0.9–1.2) | 0.9 (0.8–1.0) | < 0.001 |
 AIP | − 0.143 ± 0.158 | 0.177 ± 0.071 | 0.524 ± 0.191 | < 0.001 |
Outcome | Â | Â | Â | Â |
 Undiagnosed DM | 170 (22.4%) | 233 (30.8%) | 353 (46.6%) | < 0.001 |