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Table 3 Associations between TyG index and PCAT attenuation according to different diabetes statuses

From: Insulin resistance and coronary inflammation in patients with coronary artery disease: a cross-sectional study

Characteristics

Model 1

Model 2

Model 3

β (95% CI)

P value

β (95% CI)

P value

β (95% CI)

P value

Normoglycemia (n = 241)

      

 TyG index (per SD)

1.679 (-0.114, 3.473)

0.067

2.038 (0.279, 3.798)

0.023

1.405 (-0.401, 3.211)

0.127

TyG index (tertiles)

   

 Low level

1 (Reference)

1 (Reference)

1 (Reference)

 Moderate level

3.204 (-0.280, 6.688)

0.072

3.386 (0.010, 6.762)

0.049

2.437 (-0.914, 5.789)

0.154

 High level

0.622 (-2.862, 4.106)

0.726

1.026 (-2.413, 4.465)

0.559

0.087 (-3.367, 3.541)

0.961

 P value for trend

0.797

0.598

0.932

Pre-diabetes mellitus (n = 88)

      

 TyG index (per SD)

3.157 (0.795, 5.519)

0.009

3.089 (0.531, 5.646)

0.018

2.652 (0.060, 5.245)

0.045

TyG index (tertiles)

   

 Low level

1 (Reference)

1 (Reference)

1 (Reference)

 Moderate level

5.308 (0.871, 9.745)

0.019

5.439 (1.038, 9.840)

0.015

4.385 (-0.059, 8.830)

0.053

 High level

6.339 (1.940, 10.739)

0.005

6.691 (2.082, 11.300)

0.004

5.718 (1.066, 10.370)

0.016

 P value for trend

0.005

0.005

0.015

Diabetes mellitus (n = 240)

      

 TyG index (per SD)

1.743 (0.613, 2.874)

0.002

1.930 (0.750, 3.109)

0.001

1.825 (0.643, 3.007)

0.002

TyG index (tertiles)

   

 Low level

1 (Reference)

1 (Reference)

1 (Reference)

 Moderate level

2.332 (-0.719, 5.384)

0.134

2.407 (-0.641, 5.455)

0.122

2.155 (-0.899, 5.208)

0.167

 High level

3.992 (0.950, 7.034)

0.010

4.265 (1,161, 7.369)

0.007

4.112 (1.041, 7.184)

0.009

 P value for trend

0.011

0.008

0.009

  1. Model 1: unadjusted;
  2. Model 2: adjusted for age and sex;
  3. Model 3: adjusted for age, sex, BMI, smoking, hypertension, eGFR, antiplatelet drug use, statin drug use, ACEI/ARB drug use, beta-blocker drug use, and antidiabetic drug use
  4. TyG, triglyceride-glucose; PCAT, pericoronary adipose tissue; CI, confidence interval; SD, standard deviation; BMI, body mass index; eGFR, estimated glomerular filtration rate; ACEI, angiotensin-converting enzyme inhibitor; ARB, angiotensin receptor blocker