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Table 1 Baseline characteristics of patients grouped according to TyG-BMI index quartiles

From: The association between triglyceride glucose-body mass index and all-cause mortality in critically ill patients with atrial fibrillation: a retrospective study from MIMIC-IV database

Variables

Q 1

< 233.94 (N = 627)

Q 2

233.94–274.70 (N = 628)

Q 3

274.70-325.91 (N = 627)

Q 4

> 325.91 (N = 627)

P

Demographics

     

Age, years

77.36 ± 12.20

75.55 ± 10.74

72.82 ± 10.74

67.30 ± 11.26

< 0.01

Male, n (%)

353 (56.3)

401 (63.9)

421 (67.1)

380 (60.6)

< 0.01

Weight, Kg

64.05 ± 11.19

77.24 ± 11.50

89.42 ± 12.85

113.83 ± 25.42

< 0.01

Race, White

448 (71.5%)

480 (76.4%)

472 (75.3%)

438 (69.9%)

0.08

Height, cm

168.95 ± 10.41

169.36 ± 10.92

170.52 ± 10.48

169.92 ± 11.15

0.06

BMI, Kg/m2

22.33 ± 2.50

26.81 ± 1.88

30.63 ± 2.34

39.43 ± 8.19

< 0.01

Smoking, n (%)

39 (6.2)

33 (5.3)

32 (5.1)

33 (5.3)

0.81

Past history, n (%)

     

AMI

450 (71.8%)

507 (80.7%)

513 (81.8%)

504 (80.4%)

< 0.01

Hypertension

450 (71.8%)

507 (80.7%)

513 (81.8%)

504 (80.4%)

< 0.01

Diabetes

125 (19.9%)

171 (27.2%)

253 (40.4%)

320 (51%)

< 0.01

COPD

209 (33.3%)

163 (26%)

177 (28.2%)

198 (31.6%)

0.02

CHF

308 (49.1%)

288 (45.9%)

316 (50.4%)

323 (51.5%)

0.21

PVD

123 (19.6%)

112 (17.8%)

122 (19.5%)

101 (16.1%)

0.33

CVD

162 (25.8%)

146 (23.2%)

141 (22.5%)

117 (18.7%)

0.02

Dementia

32 (5.1%)

23 (3.7%)

23 (3.7%)

11 (1.8%)

0.02

Rheumatic disease

25 (4%)

16 (2.5%)

31 (4.9%)

26 (4.1%)

0.17

Vital signs

     

SBP, mmHg

121.59 ± 25.68

122.11 ± 24.31

119.46 ± 22.70

120.61 ± 25.13

0.24

DBP, mmHg

64.82 ± 16.87

65.47 ± 18.28

64.98 ± 17.64

66.70 ± 18.66

0.24

MBP, mmHg

81.78 ± 17.13

82.29 ± 18.32

80.93 ± 18.91

82.50 ± 18.91

0.43

HR, beats/min

85.45 ± 19.91

85.47 ± 20.24

87.87 ± 20.04

88.44 ± 21.01

0.01

RR, times/min

18.22 ± 5.70

18.08 ± 5.96

18.43 ± 5.58

18.67 ± 5.72

0.29

Medication, n (%)

     

Aspirin

475 (75.8%)

500 (79.6%)

512 (81.7%)

459 (73.2%)

< 0.01

Clopidogrel

107 (17.1%)

101 (16.1%)

93 (14.8%)

78 (12.4%)

0.12

Beta blockers

538 (85.8%)

561 (89.3%)

567 (90.4%)

540 (86.1%)

0.02

ACEI/ARB

55 (8.8%)

54 (8.6%)

54 (8.6%)

40 (6.4%)

0.35

CCB

67 (10.7%)

63 (10%)

70 (11.2%)

74 (11.8%)

0.78

Digitalis

96 (15.3%)

76 (12.1%)

84 (13.4%)

79 (12.6%)

0.36

Diuretics

481 (76.7%)

531 (84.6%)

534 (85.2%)

539 (86%)

< 0.01

Amiodarone

286 (45.6%)

297 (47.3%)

309 (49.3%)

298 (47.5%)

0.64

Insulin

374 (59.6%)

437 (69.6%)

451 (71.9%)

477 (76.1%)

< 0.01

Statin

391 (62.4%)

425 (67.7%)

456 (72.7%)

404 (64.4%)

< 0.01

Dabigatran

9 (1.4%)

9 (1.4%)

13 (2.1%)

13 (2.1%)

0.69

Rivaroxaban

20 (3.2%)

16 (2.5%)

22 (3.5%)

23 (3.7%)

0.69

Heparin

521 (83.1%)

518 (82.5%)

545 (86.9%)

555 (88.5%)

< 0.01

Warfarin

276 (44%)

294 (46.8%)

320 (51%)

294 (46.9%)

0.10

Laboratory data

     

SpO2, %

99.00 (96.00 to 100.00)

99.00 (96.00 to 100.00)

99.00 (95.00 to 100.00)

98.00 (95.00 to 100.00)

< 0.01

PO2, mmHg

223.50 (72.00 to 399.00)

259.00 (81.50 to 395.00)

195.00 (74.00 to 370.00)

131.00 (65.00 to 312.00)

< 0.01

PaCO2, mmHg

40.00 (36.00 to 45.00)

40.00 (36.00 to 45.00)

41.00 (37.00 to 47.00)

44.00 (39.00 to 51.00)

< 0.01

pH

7.40 (7.34 to 7.44)

7.40 (7.35 to 7.44)

7.38 (7.33 to 7.42)

7.36 (7.30 to 7.41)

< 0.01

BE, mmol/L

0.00 (-2.00 to 2.00)

0.00 (-2.00 to 2.00)

0.00 (-2.00 to 1.00)

0.00 (-3.00 to 2.00)

0.04

Anion gap, mmol/L

14.43 ± 4.61

14.33 ± 4.47

14.77 ± 4.76

15.33 ± 4.90

< 0.01

Bicarbonate, mmol/L

23.49 ± 4.49

23.36 ± 4.46

22.72 ± 4.36

23.49 ± 5.05

0.01

Glucose, g/dL

116.00 (99.00 to 142.00)

125.00 (105.00 to 151.00)

129.00 (109.00 to 169.00)

143.00 (117.00 to 195.50)

< 0.01

BUN, mg/dL

21.00 (15.00 to 32.00)

21.00 (15.00 to 33.00)

22.00 (16.00 to 36.00)

23.00 (16.00 to 38.50)

< 0.01

Calcium, mg/dL

8.48 ± 0.78

8.48 ± 0.84

8.43 ± 0.85

8.43 ± 0.96

0.63

Chloride, mEq/L

104.31 ± 6.86

104.33 ± 6.73

104.36 ± 6.34

102.84 ± 6.87

< 0.01

Creatinine, mg/dL

1.00 (0.70 to 1.40)

1.00 (0.80 to 1.50)

1.10 (0.90 to 1.60)

1.20 (0.90 to 1.80)

< 0.01

Sodium, mEq/L

138.57 ± 5.24

138.45 ± 4.68

138.39 ± 4.60

138.23 ± 5.12

0.69

Potassium, mEq/L

4.32 ± 0.80

4.29 ± 0.80

4.40 ± 0.82

4.44 ± 0.90

< 0.01

PT, s

15.20 (12.90 to 18.40)

15.10 (13.10 to 18.30)

14.80 (12.90 to 18.30)

14.95 (13.20 to 17.50)

0.71

PTT, s

32.25 (28.20 to 39.40)

32.30 (28.00 to 40.30)

31.70 (27.50 to 41.70)

30.80 (27.30 to 37.10)

0.02

Hematocrit, %

32.39 ± 6.98

32.58 ± 7.10

33.39 ± 7.33

33.78 ± 7.37

< 0.01

Hemoglobin, g/dL

10.60 ± 2.30

10.75 ± 2.39

10.95 ± 2.52

10.99 ± 2.44

0.01

Platelets, K/µL

211.96 ± 113.94

198.29 ± 103.58

201.86 ± 90.88

206.65 ± 88.60

0.08

WBC, K/µL

11.74 ± 7.21

11.75 ± 5.67

12.41 ± 5.65

13.24 ± 6.90

< 0.01

Lymphocytes, K/µL

1.35 ± 0.92

1.51 ± 0.92

1.65 ± 1.24

1.62 ± 1.25

< 0.01

Neutrophils, K/µL

10.03 ± 7.30

9.66 ± 5.08

10.46 ± 5.55

11.11 ± 6.24

< 0.01

MCH, pg

30.09 ± 2.47

30.27 ± 2.45

29.82 ± 2.51

29.55 ± 2.45

< 0.01

MCHC, %

32.77 ± 1.66

33.06 ± 1.62

32.83 ± 1.61

32.55 ± 1.75

< 0.01

MCV, fL

91.88 ± 6.53

91.62 ± 6.42

90.87 ± 6.49

90.87 ± 6.84

< 0.01

RBC, K/µL

3.54 ± 0.78

3.57 ± 0.79

3.69 ± 0.84

3.74 ± 0.83

< 0.01

RDW, %

14.83 ± 2.01

14.66 ± 1.91

14.82 ± 2.14

14.88 ± 1.91

0.21

HbA1c

5.97 ± 0.93

6.16 ± 1.28

6.44 ± 1.30

6.89 ± 1.79

< 0.01

HDL, mg/dL

51.00 (41.00 to 63.00)

47.00 (38.00 to 59.00)

43.00 (35.00 to 56.00)

41.00 (33.00 to 52.00)

< 0.01

LDL, mg/dL

81.00 (59.00 to 104.00)

79.00 (57.00 to 107.00)

82.00 (60.00 to 103.00)

84.00 (61.00 to 112.00)

0.47

TG, mg/dL

82.00 (63.00 to 115.00)

104.00 (77.00 to 142.00)

122.00 (88.00 to 173.00)

155.00 (106.00 to 227.50)

< 0.01

TC, mg/dL

155.00 (124.00 to 184.00)

151.00 (124.00 to 189.00)

153.00 (126.00 to 186.00)

159.00 (131.50 to 195.50)

0.01

TyG-BMI

209.38 (193.71 to 222.77)

255.10 (244.86 to 263.84)

297.11 (285.16 to 310.74)

373.57 (345.04 to 418.95)

< 0.01

GCS

14.00 (10.00 to 15.00)

14.00 (10.00 to 15.00)

14.00 (10.00 to 15.00)

14.00 (9.00 to 15.00)

0.80

SAPSII

39.00 (32.00 to 46.00)

38.00 (31.00 to 47.00)

39.00 (31.00 to 49.00)

39.00 (31.00 to 49.00)

0.54

SOFA

5.00 (3.00 to 7.00)

5.00 (3.00 to 8.00)

6.00 (4.00 to 9.00)

6.00 (4.00 to 10.00)

< 0.01

Event, n (%)

     

Cardiac arrest

21 (3.3%)

26 (4.1%)

29 (4.6%)

33 (5.3%)

0.40

Cardiogenic shock

55 (8.8%)

50 (8%)

70 (11.2%)

58 (9.3%)

0.25

Length of stay (LOS)

     

LOS in hospital

9.16 (5.99 to 14.77)

9.12 (6.07 to 15.73)

10.27 (6.43 to 15.94)

10.87 (6.63 to 17.55)

< 0.01

LOS in ICU

3.04 (1.77 to 6.05)

3.40 (1.82 to 6.69)

3.58 (2.03 to 7.52)

4.13 (2.02 to 8.82)

< 0.01

Outcome

     

30-day mortality, n (%)

116 (18.5%)

77 (12.3%)

78 (12.4%)

82 (13.1%)

< 0.01

90-day mortality, n (%)

161 (25.7%)

110 (17.5%)

102 (16.3%)

107 (17.1%)

< 0.01

180-day mortality, n (%)

191 (30.5%)

138 (22.0%)

131 (20.9%)

121 (19.3%)

< 0.01

365-day mortality, n (%)

227 (36.2%)

158 (25.2%)

153 (24.4%)

144 (23.0%)

< 0.01

  1. Continuous variables are presented as mean ± SD if normally distributed, and median (interquartile range) if not normally distributed. Categorical variables are presented as number of patients (%). BMI, body mass index; AMI, acute myocardial infarction; COPD, chronic obstructive pulmonary disease; CHF, congestive heart failure; PVD, peripheral vascular disease; CVD, cerebrovascular disease; SBP, systolic blood pressure; DBP, diastolic blood pressure; MBP, mean blood pressure; HR, heart rate; RR, respiratory rate; PaCO2, carbon dioxide partial pressure; PaO2, partial pressure of arterial oxygen; BE, base excess; BUN, urea nitrogen; PT, prothrombin time; PTT, partial prothrombin time; WBC, white blood cell; MCH, mean corpuscular hemoglobin; MCHC, mean corpusular hemoglobin concerntration; MCV, mean corpuscular volume; RBC, red blood cell; RDW, red cell distribution width; HDL, high density lipoprotein; LDL, low density lipoprotein; TC, total cholesterol; TG, triglyceride; GCS, Glasgow coma scale; SOFA, sequential organ failure assessment; SAPS II, simplified acute physiology score
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Cardiovascular Diabetology

ISSN: 1475-2840