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Table 2 Association between the MRS for T2D and phenotypes in EPIPREG and EPIDG

From: DNA methylation risk score for type 2 diabetes is associated with gestational diabetes

 

Model

Estimate

Std.Error

df

t.value

P.val

HOMA-IR

Unadjusted

0.989

0.802

0.0479

1.23

2.18E-01

C-peptide

0.422

0.167

0.0483

2.535

0.0116

Fasting glucose

0.8351

0.2726

0.0279

3.064

0.0024

2 h glucose

0.751

0.707

0.451

1.063

0.2882

HOMA-IR

Adjusted*

0.416

0.777

0.0468

0.536

0.592

C-peptide

0.254

0.152

0.0478

1.67

0.0964

Fasting glucose

0.707

0.268

0.0313

2.641

0.00869

2 h glucose

0.389

0.701

0.512

0.568

0.57

  1. HOMA-IR: Homeostatic Model Assessment of Insulin Resistance. Gluc.0: fasting glucose; 2h Gluc: glucose level after 2h from the OGTT. *Model adjusted for age, prepregnant BMI, family history of diabetes and smoking status