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Table 3 Multiple-adjusted HRs (and 95% CIs) for all-cause, CVD and non-CVD mortality across tertiles of triglyceride glucose index stratified by sex

From: Association of the triglyceride glucose index with all-cause and cardiovascular mortality in a general population of Iranian adults

All-cause mortality

Model 1

Model 2

Model 3

Model 4

Model 5

Model 6

Females

Tertile 1

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

Tertile 2

1.49(1.04,2.14)

1.01(0.70, 1.45)

0.99(0.69, 1.42)

1.01(0.70, 1.45)

1.15(0.78, 1.68)

1.13(0.77, 1.66)

Tertile 3

1.74(1.23,2.46)

1.14(0.80, 1.61)

1.11(0.79, 1.58)

1.14(0.80, 1.62)

1.37(0.94, 2.00)

1.18(0.79, 1.76)

P trend

0.002

0.430

0.502

0.419

0.094

0.424

Males

Tertile 1

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

Tertile 2

0.93(0.69, 1.25)

1.06(0.79, 1.44)

1.08(0.80, 1.46)

1.11(0.82, 1.50)

1.06(0.77, 1.45)

1.02(0.74, 1.41)

Tertile 3

1.13(0.85,1.50)

1.34(1.01, 1.78)

1.39(1.04, 1.86)

1.42(1.06, 1.90)

1.38(0.99, 1.92)

1.06(0.74, 1.51)

P trend

0.378

0.042

0.024

0.018

0.056

0.760

CVD mortality

 Females

Tertile 1

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

Tertile 2

2.19(1.13, 4.25)

1.47(0.75,2.85)

1.45(0.75, 2.83)

1.44(0.74, 2.80)

1.39(0.69, 2.81)

1.35(0.67,2.74)

Tertile 3

2.49(1.30,4.76)

1.63(0.85,3.13)

1.59(0.83, 3.03)

1.57(0.82, 3.02)

1.58(0.78, 3.18)

1.17(0.56,2.47)

P trend

0.007

0.151

0.185

0.189

0.217

0.773

 Males

Tertile 1

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

Tertile 2

1.21(0.73, 1.99)

1.41(0.85,2.32)

1.45(0.88, 2.40)

1.51(0.91, 2.50)

1.30(0.76, 2.20)

1.20(0.70,2.04)

Tertile 3

1.60(1.00, 2.55)

1.91(1.20,3.06)

1.90(1.18, 3.06)

1.96(1.21, 3.17)

1.58(0.92, 2.71)

1.01(0.56,1.83)

P trend

0.043

 < 0.001

0.008

0.006

0.099

0.995

Non-CVD mortality

 Females

Tertile 1

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

Tertile 2

1.25(0.81, 1.93)

0.85(0.55, 1.31)

0.83(0.54, 1.29)

0.86(0.55, 1.32)

1.04(0.66, 1.66)

1.04(0.66, 1.65)

Tertile 3

1.48(0.98, 2.24)

0.97(0.64, 1.47)

0.95(0.63, 1.44)

0.98(0.65, 1.49)

1.27(0.81, 2.01)

1.19(0.73, 1.92)

P trend

0.063

0.955

0.894

0.988

0.271

0.471

 Males

Tertile 1

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

Tertile 2

0.80(0.55, 1.17)

0.91(0.62, 1.33)

0.91(0.62, 1.33)

0.93(0.64, 1.36)

0.94(0.63, 1.40)

0.93(0.62, 1.38)

Tertile 3

0.91(0.64, 1.30)

1.08(0.75, 1.54)

1.15(0.80, 1.66)

1.16(0.80, 1.68)

1.28(0.84, 1.96)

1.11(0.71, 1.75)

P trend

0.613

0.700

0.470

0.440

0.265

0.681

  1. Model 1: crude
  2. Model 2: adjusted for age (years)
  3. Model 3: Additionally adjusted for education level (0–5 years/6–12 years/ > 12 years), marital status (married/not married), residency location (urban/rural)
  4. Model 4: Additionally adjusted for global dietary index (GDI), smoking status (never have smoked/have ever smoked), and total daily physical activity (METs-min/day)
  5. Model 5: Additionally adjusted for BMI (kg/m2), hypertension (yes/no), and high total cholesterol (yes/no)
  6. Model 6: Additionally adjusted for diabetes mellitus (DM) (yes/no)
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Cardiovascular Diabetology

ISSN: 1475-2840