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Table 1 Baseline characteristics of study population

From: Simultaneous assessment of stress hyperglycemia ratio and glycemic variability to predict mortality in patients with coronary artery disease: a retrospective cohort study from the MIMIC-IV database

Variables

Survivors (n = 2385)

Non-survivors (n = 404)

p-value

Demographics

   

 Age, years

68.8 ± 11.4

74.5 ± 11.8

< 0.001

 Age ≥ 75 years, n (%)

741 (31.1)

216 (53.5)

< 0.001

 Female, n (%)

680 (28.5)

159 (39.4)

< 0.001

 Body mass index, kg/m2

29.5 ± 5.9

28.8 ± 7.2

0.115

Vital signs

   

 Systolic blood pressure, mmHg

118.8 ± 21.6

120.8 ± 25.2

0.124

 Diastolic blood pressure, mmHg

63.7 ± 15.5

66.7 ± 19.6

0.003

 Heart rate, bpm

82.3 ± 14.4

87.6 ± 19.7

< 0.001

Comorbidities

   

 AMI, n (%)

1176 (49.3)

304 (75.2)

< 0.001

 Hypertension, n (%)

1908 (80.0)

348 (86.1)

0.005

 Diabetes, n (%)

1112 (46.6)

214 (53.0)

0.021

 History of MI, n (%)

399 (16.7)

61 (15.1)

0.457

 Chronic heart failure, n (%)

887 (37.2)

262 (64.9)

< 0.001

 Peripheral vascular disease, n (%)

368 (15.4)

88 (21.8)

0.002

 Cerebrovascular disease, n (%)

329 (13.8)

113 (28.0)

< 0.001

 Chronic kidney disease, n (%)

722 (30.3)

263 (65.1)

< 0.001

Treatment during hospitalization

   

 Antiplatelets, n (%)

2055 (86.2)

331 (82.1)

0.038

 Statins, n (%)

1838 (77.1)

298 (73.9)

0.187

 ACEIs/ARBs, n (%)

648 (27.2)

90 (22.3)

0.048

 Beta-blockers, n (%)

1240 (52.0)

216 (53.6)

0.593

 Vasoactive drugs, n (%)

1572 (65.9)

258 (63.9)

0.456

 Insulin, n (%)

1405 (58.9)

230 (56.9)

0.489

 Other antidiabetic drugs, n (%)

160 (6.7)

12 (3.0)

0.005

 Renal replacement therapy, n (%)

103 (4.3)

79 (19.6)

< 0.001

 Ventilation, n (%)

1885 (79.0)

288 (71.3)

0.001

Laboratory measurements

   

 Serum creatinine, mg/dL

1.0 (0.8–1.3)

1.4 (1.0–2.0)

< 0.001

 eGFR, mL/min/1.73m2

76.3 (55.9–96.4)

48.4 (32.5–68.5)

< 0.001

 White blood cells, 109/L

10.8 (7.9–14.6)

11.7 (8.6–15.8)

0.005

 Hemoglobin, g/dL

11.0 ± 2.5

10.7 ± 2.3

0.034

 Platelets, 109/L

196.4 ± 82.4

223.1 ± 102.3

< 0.001

 Glucose, mg/dL

137.0 (115.0-178.0)

178.0 (133.5–260.0)

< 0.001

 HbA1c, %

6.6 ± 1.6

6.6 ± 1.5

0.453

 SHR, (mean ± standard deviation)

1.1 ± 0.5

1.3 ± 0.6

< 0.001

 GV, %

20.0 (12.9–30.6)

25.2 (16.9–36.7)

< 0.001

 Length of ICU stay, days

3.0 (2.0–4.0)

4.0 (2.0–7.0)

< 0.001

 SOFA score, (mean ± standard deviation)

5.0 (3.0–7.0)

6.0 (4.0–8.0)

< 0.001

  1. Abbreviations: ACEIs/ARBs, angiotensin-converting enzyme inhibitors/angiotensin receptor blockers; AMI, acute myocardial infarction; eGFR, estimated glomerular filtration rate; GV, glycemic variability; HbA1c, glycated hemoglobin A1c; ICU, intensive care unit; MI, myocardial infarction; SHR, stress hyperglycemia ratio; SOFA, Sequential Organ Failure Assessment