Table 1 Baseline clinical characteristics stratified according diabetic status and type of lesion (de-novo lesions vs. ISR)
|  | Overall population (N = 2,083) | Patents with de-novo lesions (N = 1,173) | Patients with ISR (N = 910) | ||||||
|---|---|---|---|---|---|---|---|---|---|
|  | Patients with DM (N = 864) | Patients without DM (N = 1,219) | p-value | Patients with DM (N = 452) | Patients without DM (N = 721) | p-value | Patients with DM (N = 412) | Patients without DM (N = 498) | p-value |
Male (%) | 691 (80.0) | 999 (82.0) | 0.281 | 358 (79.2) | 599 (83.1) | 0.112 | 333 (80.8) | 400 (80.3) | 0.915 |
Age, mean (SD) | 67.21 (10.39) | 66.19 (11.84) | 0.043 | 65.08 (11.11) | 64.42 (12.21) | 0.353 | 69.53 (8.99) | 68.77 (10.79) | 0.257 |
Insulin dependent (%) | 283 (32.8) | 0 (0.0) | < 0.001 | 120 (26.5) | 0 (0.0) | < 0.001 | 163 (39.6) | 0 (0.0) | < 0.001 |
Hypercholesterolemia (%) | 683 (79.1) | 813 (66.7) | < 0.001 | 345 (76.3) | 441 (61.2) | < 0.001 | 338 (82.0) | 372 (74.7) | 0.010 |
Hypertension (%) | 711 (82.3) | 893 (73.3) | < 0.001 | 343 (75.9) | 497 (68.9) | 0.012 | 368 (89.3) | 396 (79.5) | < 0.001 |
Prior MI (%) | 391 (45.3) | 503 (41.3) | 0.077 | 152 (33.6) | 209 (29.0) | 0.107 | 239 (58.0) | 294 (59.0) | 0.806 |
Prior CABG (%) | 109 (12.6) | 135 (11.1) | 0.313 | 35 (7.7) | 46 (6.4) | 0.437 | 74 (18.0) | 89 (17.9) | 0.999 |
Prior PCI (%) | 605 (70.0) | 775 (63.6) | 0.003 | 206 (45.6) | 297 (41.2) | 0.157 | 399 (96.8) | 478 (96.0) | 0.608 |
Multivessel disease (%) | 542 (62.7) | 693 (56.8) | 0.008 | 258 (57.1) | 373 (51.7) | 0.084 | 284 (68.9) | 320 (64.3) | 0.157 |
Heart Failure (%) | 90 (10.4) | 80 (6.6) | 0.002 | 40 (8.8) | 36 (5.0) | 0.013 | 50 (12.1) | 44 (8.8) | 0.129 |
LVEF, mean (SD) | 50.63 (11.43) | 52.51 (10.69) | < 0.001 | 50.94 (11.88) | 53.07 (11.22) | 0.003 | 50.31 (10.93) | 51.73 (9.87) | 0.042 |
Creatinine mg/ml, median [IQR] | 1.02 [0.86. 1.30] | 0.98 [0.82. 1.13] | < 0.001 | 1.01 [0.84. 1.28] | 0.97 [0.82. 1.10] | < 0.001 | 1.03 [0.87. 1.35] | 1.00 [0.81. 1.19] | 0.001 |
Hb g/dl, mean (SD) | 13.04 (2.30) | 13.63 (1.99) | < 0.001 | 13.23 (2.28) | 13.70 (2.02) | < 0.001 | 12.84 (2.31) | 58.70 (1007.64) | 0.356 |
Clinical presentation | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 Stable Angina, (%) | 299 (34.6) | 407 (33.4) | 0.089 | 152 (33.6) | 227 (31.5) | 0.260 | 147 (35.7) | 180 (36.1) | 0.035 |
 Silent Ischemia (%) | 151 (17.5) | 258 (21.2) |  | 83 (18.4) | 171 (23.7) |  | 68 (16.5) | 87 (17.5) |  |
 Unstable Angina (%) | 144 (16.7) | 220 (18.0) |  | 61 (13.5) | 95 (13.2) |  | 83 (20.1) | 125 (25.1) |  |
 NSTEMI (%) | 207 (24.0) | 238 (19.5) |  | 104 (23.0) | 153 (21.2) |  | 103 (25.0) | 85 (17.1) |  |
 STEMI, < 12 h (%) | 38 (4.4) | 53 (4.3) |  | 31 (6.9) | 36 (5.0) |  | 7 (1.7) | 17 (3.4) |  |
 STEMI, > 12 h (%) | 25 (2.9) | 43 (3.5) |  | 21 (4.6) | 39 (5.4) |  | 4 (1.0) | 4 (0.8) |  |