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Table 3 Risk factors in the development of vascular events

From: Independent association of thigh muscle fat density with vascular events in Korean adults

 

Men (N = 1,880)

Women (N = 1,715)

 

Univariable

Multivariable

Univariable

Multivariable

 

Unadjusted

P

Adjusted HR

P

Unadjusted

P

Adjusted HR

P

HR (95% CI)

(95% CI)

HR (95% CI)

(95% CI)

LDM/NDM ratio (%)

1.06 (1.04–1.07)

< 0.001

1.04 (1.02–1.06)

< 0.001

1.04 (1.03–1.05)

< 0.001

1.02 (1.01–1.04)

0.001

Age (years)

1.04 (1.03–1.06)

< 0.001

1.06 (1.04–1.08)

< 0.001

1.07 (1.05–1.09)

< 0.001

1.08 (1.05–1.11)

< 0.001

HbA1c (%)

1.32 (1.22–1.43)

< 0.001

1.29 (1.14–1.45)

< 0.001

1.36 (1.23–1.50)

< 0.001

1.43 (1.25–1.64)

< 0.001

eGFR (mL/min/1.73 m²)

0.99 (0.98–1.00)

0.195

1.01 (1.00–1.02)

0.155

0.98 (0.97–1.00)

0.019

1.00 (0.99–1.02)

0.788

hsCRP (mg/L)*

1.26 (1.17–1.36)

< 0.001

1.15 (1.06–1.25)

0.001

1.30 (1.17–1.45)

< 0.001

1.09 (0.96–1.24)

0.163

Visceral adipose tissue (cm2)

1.00 (1.00–1.00)

< 0.001

1.00 (1.00–1.00)

0.576

1.00 (1.00–1.00)

< 0.001

1.00 (1.00–1.01)

0.848

Hypertension, yes

2.56 (1.95–3.36)

< 0.001

1.45 (1.02–2.07)

0.039

2.61 (1.74–3.92)

< 0.001

1.38 (0.87–2.21)

0.174

Dyslipidemia, yes

2.87 (2.14–3.86)

< 0.001

2.69 (1.83–3.94)

< 0.001

2.31 (1.49–3.59)

< 0.001

2.16 (1.25–3.73)

0.006

Smoking

 

0.065

 

0.064

 

0.034

 

0.032

 Never smoker

1 (Reference)

 

1 (Reference)

 

1 (Reference)

 

1 (Reference)

 

 Ex-smoker

1.07 (0.77–1.48)

0.686

1.26 (0.85–1.86)

0.243

2.00 (0.73–5.43)

0.176

3.13 (1.02–9.62)

0.046

 Current smoker

1.42 (1.01–2.01)

0.047

1.54 (0.96–2.47)

0.077

2.70 (0.85–8.56)

0.091

3.05 (0.41–22.8)

0.277

  1. CI, confidence interval; HR, hazard ratio; LDM, low density muscle; NDM, normal density muscle; hsCRP, high sensitivity C-reactive protein; eGFR, estimated glomerular filtration rate. *Log transformed for analysis