From: Independent association of thigh muscle fat density with vascular events in Korean adults
Men (N = 1,880) | Women (N = 1,715) | |||||||
---|---|---|---|---|---|---|---|---|
Univariable | Multivariable | Univariable | Multivariable | |||||
Unadjusted | P | Adjusted HR | P | Unadjusted | P | Adjusted HR | P | |
HR (95% CI) | (95% CI) | HR (95% CI) | (95% CI) | |||||
LDM/NDM ratio (%) | 1.06 (1.04–1.07) | < 0.001 | 1.04 (1.02–1.06) | < 0.001 | 1.04 (1.03–1.05) | < 0.001 | 1.02 (1.01–1.04) | 0.001 |
Age (years) | 1.04 (1.03–1.06) | < 0.001 | 1.06 (1.04–1.08) | < 0.001 | 1.07 (1.05–1.09) | < 0.001 | 1.08 (1.05–1.11) | < 0.001 |
HbA1c (%) | 1.32 (1.22–1.43) | < 0.001 | 1.29 (1.14–1.45) | < 0.001 | 1.36 (1.23–1.50) | < 0.001 | 1.43 (1.25–1.64) | < 0.001 |
eGFR (mL/min/1.73 m²) | 0.99 (0.98–1.00) | 0.195 | 1.01 (1.00–1.02) | 0.155 | 0.98 (0.97–1.00) | 0.019 | 1.00 (0.99–1.02) | 0.788 |
hsCRP (mg/L)* | 1.26 (1.17–1.36) | < 0.001 | 1.15 (1.06–1.25) | 0.001 | 1.30 (1.17–1.45) | < 0.001 | 1.09 (0.96–1.24) | 0.163 |
Visceral adipose tissue (cm2) | 1.00 (1.00–1.00) | < 0.001 | 1.00 (1.00–1.00) | 0.576 | 1.00 (1.00–1.00) | < 0.001 | 1.00 (1.00–1.01) | 0.848 |
Hypertension, yes | 2.56 (1.95–3.36) | < 0.001 | 1.45 (1.02–2.07) | 0.039 | 2.61 (1.74–3.92) | < 0.001 | 1.38 (0.87–2.21) | 0.174 |
Dyslipidemia, yes | 2.87 (2.14–3.86) | < 0.001 | 2.69 (1.83–3.94) | < 0.001 | 2.31 (1.49–3.59) | < 0.001 | 2.16 (1.25–3.73) | 0.006 |
Smoking | 0.065 | 0.064 | 0.034 | 0.032 | ||||
Never smoker | 1 (Reference) | 1 (Reference) | 1 (Reference) | 1 (Reference) | ||||
Ex-smoker | 1.07 (0.77–1.48) | 0.686 | 1.26 (0.85–1.86) | 0.243 | 2.00 (0.73–5.43) | 0.176 | 3.13 (1.02–9.62) | 0.046 |
Current smoker | 1.42 (1.01–2.01) | 0.047 | 1.54 (0.96–2.47) | 0.077 | 2.70 (0.85–8.56) | 0.091 | 3.05 (0.41–22.8) | 0.277 |