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Table 1 Pooled baseline characteristics

From: Effect of SGLT-2 inhibitors on arrhythmia events: insight from an updated secondary analysis of > 80,000 patients (the SGLT2i—Arrhythmias and Sudden Cardiac Death)

 

Total

Randomized to SGLT2i group

Randomized to control

Sample Size, n

88,098

48,585

39,513

Age, year

64.9 ± 9.4

64.6 ± 9.4

65.2 ± 9.4

Male, n (%)

55,467/88098 (63.0)

30,318/48585 (62.4)

25,149/39513 (63.6)

LVEF, %

39.2 ± 14.6

39.3 ± 14.5

39.1 ± 14.7

eGFR, ml/min/1.73 m2

67.3 ± 23.6

67.9 ± 23.5

66.6 ± 23.6

HF, n (%)

27,677/80183 (34.5)

14,327/43370 (33.0)

13,350/36813 (36.3)

DM, n (%)

78,212/88098 (88.8)

43,643/48585 (89.8)

34,569/39513 (87.5)

CKD, n (%)

14,851/17851 (83.2)

7614/9107 (83.6)

7237/8744 (82.8)

AF, n (%)

6855/16045 (42.7)

3441/8024 (42.9)

3414/8021 (42.6)

ARNi use n (%)

1975/27851 (7.1)

989/13924 (7.1)

986/13927 (7.1)

  1. LVEF left ventricular ejection fraction, eGFR estimated glomerular filtration rate, HF heart failure, DM diabetes mellitus, CKD chronic kidney disease, AF atrial fibrillation, ARNi angiotensin receptor/neprilysin inhibitor