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Table 2 Association between TyG index and adverse outcomes

From: The relationship between triglyceride-glucose index and prospective key clinical outcomes in patients hospitalised for coronary artery disease

Variables

Total incidence

Quintiles of TyG index

p for trend

 

1st quintile

(6.10–8.33)

2nd quintile

(8.33–8.67)

3rd quintile

(8.67–9.97)

4th quintile

(9.97–9.37)

5th quintile

(9.37–12.03)

 

All-cause mortality

       

Events/sample size

759/3321

180/665

157/664

134/664

137/664

151/664

 

Incidence per 1,000 PYs (95% CI)

26.17 (24.37–28.09)

31.70 (27.39–36.68)

27.40 (23.44–32.04)

22.77 (19.22–26.97)

23.38 (19.78–27.65)

25.79 (21.99–30.25)

 

Crude HR (95% CI)

1.40 (1.12–1.75)

1.20 (0.96–1.52)

Ref.

1.03 (0.81–1.31)

1.13 (0.90–1.43)

0.019

Model 1a: adjusted HR (95% CI)

1.05 (0.84–1.33)

1.03 (0.82–1.29)

Ref.

1.09 (0.85–1.38)

1.47 (1.17–1.86)

0.007

Model 2b: adjusted HR (95% CI)

1.18 (0.93–1.50)

1.12 (0.89–1.41)

Ref.

1.14 (0.89–1.45)

1.38 (1.07–1.77)

0.270

MACEs

       

Events/sample size

1291/3321

281/665

257/664

235/664

235/664

283/664

 

Incidence per 1,000 PYs (95% CI)

49.17 (46.56–51.92)

54.76 (48.72–61.55)

49.08 (43.44–55.47)

43.97 (38.70–49.97)

43.75 (38.50–49.72)

54.69 (48.68–61.45)

 

Crude HR (95% CI)

1.25 (1.05–1.49)

1.12 (0.94–1.34)

Ref.

1.01 (0.83–1.20)

1.25 (1.05–1.49)

0.558

Model 1a: adjusted HR (95% CI)

1.01 (0.85–1.21)

0.99 (0.83–1.18)

Ref.

1.01 (0.84–1.21)

1.45 (1.22–1.72)

0.001

Model 2b: adjusted HR (95% CI)

1.10 (0.92–1.31)

1.07 (0.90–1.28)

Ref.

1.02 (0.85–1.23)

1.36 (1.13–1.64)

0.101

  1. PY person-year, HR hazard ratio, CI confidence interval, MACEs major adverse cardiovascular events, TyG triglyceride-glucose, ACS acute coronary syndrome, ACE-I angiotensin-converting enzyme inhibitor, ARB angiotensin II receptor blocker, BMI body mass index, eGFR estimated glomerular filtration rate, LVEF left ventricular ejection fraction, TC total cholesterol, LDL-C low-density lipoprotein cholesterol
  2. aModel 1 adjusted for age, gender
  3. bModel 2 adjusted for age, gender, BMI, smoking, ACS, previous myocardial infarction, stroke, hypertension, diabetes mellitus, statin, beta blocker, ACE-I/ARB, LVEF, eGFR, TC, LDL-C.