Fig. 2

Box plot of the concentrations of the 13 significant proteins detected with ANOVA in the 3 groups of subjects (each group characteristics are indicated in Methods section). Refer to Table 1 for complete post-hoc comparisons between groups. The edges of the boxes indicate the 25th and 75th quantiles, including the middle 50% of the data; whiskers indicate the furthest points within 1.5 x IQR from the box. The continuous horizontal line in each graph represents the overall arithmetic mean of the data set. For graphical purpose, the full names of the proteins have been abbreviated, as reported in Table S4. Protein concentration in y-axis is expressed as a normalized value (N.V.) on the basis of internal standard. Asterisks indicate paired significant differences with Fisher’s Least Significant Difference (LSD) test at the 0.05 level or less. * comparison DC vs. DN; † comparison DN vs. NC; ‡ comparison DC vs. NC