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Table 2 Incidence of CVD and its subtypes according to multi-trajectory of TyG levels and lifestyle scores

From: Multi-trajectories of triglyceride-glucose index and lifestyle with Cardiovascular Disease: a cohort study

 

Multi-trajectory of TyG levels and lifestyle scores, HR (95% CI)

 

Group 1

Group 2

Group 3

Group 4

Group 5

CVD

     

N/n

616/10,469

482/6559

510/11,974

1124/15,621

310/2761

Incidence rate*

5.60(5.18–6.06)

7.03(6.43–7.69)

4.09(3.75–4.46)

7.02(6.62–7.44)

11.22(10.03–12.54)

Model 1

1.44(1.28–1.63)

1.98(1.74–2.25)

Reference

1.65(1.48–1.83)

2.72(2.36–3.13)

Model 2

1.44(1.27–1.62)

1.83(1.61–2.09)

Reference

1.53(1.38–1.71)

2.41(2.09–2.79)

Model 3

1.33(1.17–1.50)

1.45(1.26–1.66)

Reference

1.32(1.18–1.47)

1.76(1.50–2.05)

Stroke

     

N/n

522/10,469

396/6559

428/11,974

882/15,621

253/2761

Incidence rate*

4.73(4.34–5.15)

5.74(5.20–6.33)

3.42(3.11–3.76)

5.47(5.12–5.84)

9.06(8.01–10.25)

Model 1

1.47(1.28–1.68)

1.95(1.69–2.24)

Reference

1.53(1.36–1.72)

2.63(2.25–3.07)

Model 2

1.46(1.28–1.67)

1.81(1.56–2.09)

Reference

1.43(1.27–1.61)

2.34(1.99–2.74)

Model 3

1.35(1.18–1.54)

1.44(1.24–1.68)

Reference

1.24(1.10–1.39)

1.73(1.46–2.06)

Myocardial infarction

     

N/n

102/10,469

94/6559

89/11,974

266/15,621

65/2761

Incidence rate*

0.91(0.75–1.11)

1.34(1.09–1.64)

0.70(0.57–0.87)

1.63(1.44–1.83)

2.27(1.78–2.90)

Model 1

1.31(0.98–1.75)

2.10(1.55–2.84)

Reference

2.21(1.74–2.81)

3.15(2.29–4.34)

Model 2

1.30(0.97–1.74)

1.93(1.42–2.62)

Reference

2.05(1.61–2.62)

2.79(2.01–3.87)

Model 3

1.21(0.90–1.63)

1.49(1.09–2.04)

Reference

1.72(1.34–2.21)

1.86(1.31–2.64)

  1. *Cases per 1000 person-years
  2. Model 1 adjusted for age and sex
  3. Model 2 included covariates in model 1 and marital status, education background, BMI
  4. Model 3 included covariates in model 2 and LDL-C, HDL-C, Hs-CRP, eGFR, hypertension, diabetes mellitus, and use of antihypertensive, hypoglycemic, and hypolipidemic medications