Exenatide (n = 19) | Control (n = 17) | P value | |
---|---|---|---|
Stent length by OCT, mm | 26.3 (20.0–31.4) | 28.6 (24.0–40.0) | 0.241a |
Number of frames per pullback, n | 539 (374–540) | 539 (374–540) | 0.742a |
Reference segments | |||
CS lumen area proximal reference, mm2 | 9.6 (7.6–12.6) | 8.7 (5.9–11.0) | 0.158a |
Minimal Lumen Diameter at proximal reference, mm | 3 (2.7–3.5) | 3 (2.5–3.5) | 0.384a |
CS lumen area distal reference, mm2 | 5.7 (4.6–8.5) | 5 (3.3–6.9) | 0.334a |
Minimal Lumen Diameter at distal reference, mm | 2.6 (2–3.1) | 2.3 (1.8–2.8) | 0.261a |
Dissection at proximal stent edge, n (%) | 0 (0.0) | 1 (5.9) | 0.472b |
Mean dissection length at proximal stent edge, mm | 0 (0.0) | 0.05 (0.2) | 0.290b |
Dissection at distal stent edge, n (%) | 2 (10.5) | 1 (5.9) | 1.000b |
Mean dissection’s length at distal stent edge, mm | 8.4 (7.7–15) | 12.1 (7.5–13.2) | 0.667a |
Stenosis segment | |||
CS lumen area at maximal obstruction, mm2 | 6.1 (1.8) | 5.1 (1.8) | 0.122c |
Lumen area stenosis (mean area as reference), % | 23.2 (3.6–32.7) | 17.3 (10–27.8) | 0.692a |
CS stent area at maximal obstruction, mm2 | 6.1 (1.8) | 5.1 (1.8) | 0.097c |
MSA in proximal stent half segment, mm2 | 7.03 (1.8) | 5.9 (1.8) | 0.073c |
MSA in distal stent half segment, | 6.1 (2.0) | 4.8 (1.7) | 0.107c |
Mean in-stent CS area, mm2 | 8.1 (2.2) | 7 (2.0) | 0.134c |
Stent expansion at MSA, % | 75.1 (57.4–87.8) | 70.4 (57.7–86.9) | 0.704c |
Mean stent expansion, % | 116.6 (24.0) | 115.9 (18.7) | 0.784c |
In-stent stent volume, mm3 | 157.4 (136–273) | 166.5 (104.8–258) | 0.537a |
Vessel characterization at MSA | |||
Plaque characterization | 0.280b | ||
Fibrotic,n (%) | 0 (0.0) | 0 (0.0) | |
Lipidic, n (%) | 4 (21.1) | 5 (29.4) | |
Mixed non-calcified, n (%) | 4 (21.1) | 7 (41.2) | |
Mixed calcified, n (%) | 9 (47.4) | 3 (17.6) | |
Calcification arc, degrees | 65.6 (71) | 30.6 (51.5) | 0.104c |
Calcification deep, mm | 0.4 (0.4) | 0.2 (0.4) | 0.340c |
Thrombus presence, n (%) | 7 (36.8) | 2 (11.8) | 0.128b |
Tissue prolapse, n (%) | 10 (52.6) | 8 (47.1) | 1.000b |
Major tissue prolapse, n (%) | 3 (15.8%) | 3 (17.6%) | 0.895b |
Strut analysis | |||
Total number of struts analyzed per lesion, n | 2031 (664) | 2545.5 (1187) | 0.113c |
Number of struts per cross-section, n | 10.2 (1.6) | 10.3 (1.4) | 0.863c |
Frequency of malapposed struts per lesion, % | 5.7 (1.9–12) | 5.7 (3.8–13) | 0.862a |
Malapposition > 300 µm,% | 0.79 (1.5) | 1.5 (2.7) | 0.347c |
Malapposition volume, mm3 | 11 (4.8) | 13.5 (8.4) | 0.285c |
Maximal consecutive length of malapposed struts, mm | 1.9 (1.0–3.4) | 2 (1.1–3.5) | 0.715a |