Olive oil consumption, plasma metabolites, and risk of type 2 diabetes and cardiovascular disease

Table 2 Pearson correlation coefficients between metabolomics signatures and olive oil consumption

	Baseline visit				1-year visit
Assessment	Pearson correlation (95% CI)¹	Total metabolites²	Metabolites with positive coefficients	Metabolites with negative coefficients	Pearson correlation (95% CI)¹
Total olive oil	0.40 (0.37, 0.44)	74	37	37	0.27 (0.22, 0.31)
Extra virgin olive oil	0.37 (0.33, 0.41)	78	41	37	0.23 (0.18, 0.28)
Common olive oil	0.25 (0.21, 0.29)	17	8	9	0.16 (0.12, 0.21)

¹The Pearson’s coefficients reflect the correlation between FFQ-derived olive oil consumption and predicted olive oil consumption based on the olive oil-specific multi-metabolite model identified within the discovery cohort
²Number of metabolites obtained 10 times in the tenfold cross-validation procedure for the elastic net continuous regression, using the lambda.min option
Olive oil consumption was adjusted for total energy intake by the residual method

ISSN: 1475-2840