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Fig. 3 | Cardiovascular Diabetology

Fig. 3

From: Genetic deletion of MMP12 ameliorates cardiometabolic disease by improving insulin sensitivity, systemic inflammation, and atherosclerotic features in mice

Fig. 3

Reduced systemic inflammation and altered immune cell composition in blood of DKO mice. (A) Circulating MCP-1 concentrations in LdlrKO and DKO mice measured by ELISA (n = 5–7). (B) Absolute white blood cell count analyzed by a fully automated hematology analyzer (n = 5–6). (C, D) Representative flow cytometric plots of Ly6G vs. CD11b staining of CD45 + cells. (E) Quantification of Ly6G vs. CD11b staining of immune cells in peripheral blood (n = 5–6). Data represent mean values ± SD. *p < 0.05, **p ≤ 0.01, ***p ≤ 0.001

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Cardiovascular Diabetology

ISSN: 1475-2840