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Table 1 Baseline characteristics of the study population

From: An elevated triglyceride-glucose index predicts adverse outcomes and interacts with the treatment strategy in patients with three-vessel disease

 

Normal TyG index (≤ 9.51)

Elevated TyG index (> 9.51)

P-value

n = 7672

n = 1190

Age (years)

61.4 ± 10.0

59.0 ± 9.8

 < 0.001

Male

6227 (81.2)

838 (70.4)

 < 0.001

BMI (kg/m2)

25.8 ± 3.1

26.3 ± 2.9

 < 0.001

Family history of CAD

2147 (28.0)

400 (33.6)

 < 0.001

Previous myocardial infarction

2772 (36.1)

381 (32.0)

0.006

Previous stroke

768 (10.0)

113 (9.5)

0.617

Hypertension

5157 (67.2)

835 (70.2)

0.047

Diabetes

2315 (30.2)

779 (65.5)

 < 0.001

Hyperlipidaemia

4142 (54.0)

815 (68.5)

 < 0.001

COPD

93 (1.2)

7 (0.6)

0.080

PAD

590 (7.7)

99 (8.3)

0.487

CKD

56 (0.7)

17 (1.4)

0.021

Current/former smoker

4306 (56.1)

629 (52.9)

0.037

Clinical presentation

 SAP

3070 (40.0)

430 (36.1)

0.012

 ACS

4602 (60.0)

760 (63.9)

0.012

 LVEF (%)

58.5 ± 9.3

58.3 ± 9.4

0.474

 CCr (mL/min)

84.8 ± 26.5

89.8 ± 28.7

< 0.001

 TyG index

8.76 ± 0.39

9.92 ± 0.42

< 0.001

 Left main involvement

1827 (23.8)

236 (19.8)

0.003

SYNTAX score

 ≤ 22

3027 (39.5)

497 (41.8)

0.317

 23–32

2871 (37.4)

429 (36.1)

 ≥ 33

1774 (23.1)

264 (22.2)

Treatment strategy

 CABG

2338 (30.5)

338 (28.4)

0.347

 PCI

3269 (42.6)

520 (43.7)

 MT

2065 (26.9)

332 (27.9)

Medication at discharge

 Aspirin

7327 (95.5)

1149 (96.6)

0.115

 Clopidogrel

3985 (51.9)

645 (54.2)

0.155

 ACEI

2796 (36.4)

484 (40.7)

0.005

 ARB

1151 (15.0)

196 (16.5)

0.204

 Beta-blocker

6713 (87.5)

1075 (90.3)

0.006

 CCB

2764 (36.0)

432 (36.3)

0.879

 Statin

5110 (66.6)

815 (68.5)

0.211

  1. Values are presented as mean ± standard deviation or number (%)
  2. ACEI, angiotensin-converting enzyme inhibitors; ACS, acute coronary syndrome; ARB, angiotensin II receptor blockers; BMI, body mass index; CABG, coronary artery bypass grafting; CAD, coronary artery disease; CCB, calcium channel blocker; CCr, creatinine clearance; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; LVEF, left ventricular ejection fraction; MT, medical therapy; PAD, peripheral artery disease; PCI, percutaneous coronary intervention; SAP, stable angina pectoris; TyG index, triglyceride-glucose Index