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Fig. 4 | Cardiovascular Diabetology

Fig. 4

From: Treatment with recombinant Sirt1 rewires the cardiac lipidome and rescues diabetes-related metabolic cardiomyopathy

Fig. 4

Sirt1 signalling is related to MCM features in human myocardial samples from diabetic and nondiabetic patients. A Expression levels of Sirt1 assessed by real-time PCR in myocardial samples from diabetic (n = 9) and nondiabetic (n = 9) patients. B Intramyocardial triacylglycerol levels in myocardial samples from diabetic (n = 9) and nondiabetic (n = 9) patients. C Scatterplot showing the correlation of myocardial Sirt1 levels with myocardial triacylglycerols, plasma HbA1c and fasting plasma glucose in the study population (n = 18). Data are presented as box plots showing median [IQR] and compared by the Mann–Whitney U test. Correlations between variables were assessed by Spearman’s test. *p < 0.05, **p < 0.01. T2D type 2 diabetes TAG triacylglycerols

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Cardiovascular Diabetology

ISSN: 1475-2840