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Table 3 Subgroup analysis for the effect of the TyG index and eGFR on the risk of cardiovascular diseases

From: Triglyceride-glucose index, renal function and cardiovascular disease: a national cohort study

 

Subgroup 1

Subgroup 2

HR (95% CI)

P value

HR (95% CI)

P value

TyG < median & eGFR ≥ 60

Ref

   

TyG < median & eGFR < 60

1.462 (0.783–2.648)

0.218

1.484 (0.795–2.690)

0.201

TyG ≥ median & eGFR ≥ 60

1.183 (1.052–1.330)

0.005

1.162 (1.033–1.307)

0.013

TyG ≥ median & eGFR < 60

1.928 (1.215–3.032)

0.005

1.891 (1.191–2.976)

0.006

  1. eGFR was calculated using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation; unit of eGFR: ml/minute/1.73 m2; median value of the TyG index: 8.6
  2. Age, sex, residence, marriage, education level, BMI level, smoking status, hypertension, diabetes, and nonHDL cholesterol were adjusted
  3. Subgroup 1: among 5436 participants without treatments for diabetes, hypertension or dyslipidemia at baseline; subgroup 2: among 3019 participants without treatments for diabetes, hypertension or dyslipidemia at baseline or during follow-up
  4. RR risk ratio, CI confidence interval, eGFR estimated glomerular filtration rate, TyG triglyceride-glucose index, HDL high density lipoprotein
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Cardiovascular Diabetology

ISSN: 1475-2840