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Table 8 Outcomes of the scenario analyses

From: Cost-effectiveness of finerenone in chronic kidney disease associated with type 2 diabetes in The Netherlands

Description

Incremental costs (discounted)

Incremental QALYs (discounted)

ICER (discounted)

Base case

− €6136

0.20

Dominant

The discount rate is 0% for both costs and effects

− €7957

0.23

Dominant

Utility data is based on literature retrieved in a systematic literature review

− €6136

0.19

Dominant

Utility data is based solely on trial data

− €6136

0.17

Dominant

Utility data is based on retrieved from the literature that was validated by the Dutch National Healthcare Institute

− €6136

0.19

Dominant

Patients are 45 years old at baseline

− €26,622

0.36

Dominant

Patients are 55 years old at baseline

− €17,733

0.29

Dominant

Patients are 65.8 years old at baseline (i.e., the average age of Dutch patients with T2D at CKD diagnosis)

− €5708

0.19

Dominant

The discount rate is 5% for both costs and effects

− €5766

0.14

Dominant

Time horizon 10 years

− €5396

0.11

Dominant

Solely direct dialysis costs are incorporated

− €4414

0.20

Dominant

Productivity losses are based on different sources

− €5545

0.20

Dominant

  1. CKD chronic kidney disease, ICER incremental cost-effectiveness ratio, QALYs quality-adjusted life year, T2D Type 2 Diabetes