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Table 7 Costs, QALYs, and ICER per patient over a lifetime for finerenone + SoC and SoC

From: Cost-effectiveness of finerenone in chronic kidney disease associated with type 2 diabetes in The Netherlands

 

Finerenone + SoC

SoC

Difference

Costs within the healthcare system

 Medication costs

€10,098

€6554

€3545

 CKD treatment

€4272

€4125

€148

 Dialysis

€57,650

€65,584

− €7935

 Transplant

€2262

€2125

− €275

 First CV event costs

€5843

€6134

− €291

 Subsequent CV event

€1528

€1633

− €105

 Hyperkalaemia leading to hospitalization

€159

€88

€70

 Hyperkalaemia not leading to hospitalization

€192

€126

€66

 New onset of atrial fibrillation

€168

€198

− €30

Indirect costs for patients and caregivers

€111,076

€12,4069

− €1329

Total costs (healthcare perspective)

€82,172

€86,978

− €4708

Total costs (societal perspective)

€93,248

€99,384

− €6136

Total effects (life-years without CV)

7.43

7.13

0.30

Total effects (life-years without RRT)

8.65

8.34

0.31

Total effects (life-years)

9.40

9.18

0.22

Total effects (QALY)

7.05

6.85

0.20

ICER (costs/QALY)

Finerenone + SoC is a dominant treatment option

  1. CKD chronic kidney disease, CV cardiovascular, eGFR estimated glomerular filtration rate, ICER incremental cost-effectiveness ratio, MI myocardial infarction, QALY quality-adjusted life year, RRT renal replacement therapy, SoC standard of care