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Table 1 Characteristics of the study population, total and by the presence of prevalent myocardial infarction

From: Advanced glycation end products measured by skin autofluorescence and subclinical cardiovascular disease: the Rotterdam Study

 

Total

Non-prevalent MI

Prevalent MI

N

3001

2767

229

Age, year

72.71 ± 9.36

72.40 ± 9.39

76.26 ± 8.31

Sex (female)

1,697 (57)

1,633 (59)

60 (26)

Caucasian

2,775 (96)

2,555 (96)

215 (97)

Smoking status

 Never

952 (32)

915 (33)

35 (16)

 Former

1,619 (55)

1,460 (53)

159 (72)

 Current

388 (13)

359 (13)

28 (13)

Body mass index, kg/m2

27.55 ± 4.30

27.49 ± 4.32

28.20 ± 4.01

Waist-hip ratio

0.90 ± 0.09

0.90 ± 0.09

0.96 ± 0.10

Total cholesterol, mmol/L

5.45 ± 1.10

5.52 ± 1.08

4.56 ± 1.01

HDL, mmol/L

1.44 (1.20, 1.74)

1.45 (1.20, 1.76)

1.26 (1.09, 1.48)

Triglycerides, mmol/L

1.27 (0.97, 1.72)

1.27 (0.98, 1.73)

1.28 (0.96, 1.72)

Lipid lowering medication

916 (31)

737 (27)

178 (80)

Dyslipidemia

1562 (54)

1364 (51)

197 (89)

eGFR, mL/min per 1.73 m2

74.94 (65.49, 84.46)

75.34 (65.96, 84.62)

70.16 (57.88, 81.22)

Chronic kidney disease

431 (15)

366 (14)

64 (29)

Diabetes

413 (14)

365 (13)

47 (21)

Mean intima-media thickness, mm

0.92 ± 0.16

0.92 ± 0.15

0.98 ± 0.18

Max intima-media thickness, mm

1.05 ± 0.19

1.04 ± 0.19

1.14 ± 0.23

Pulse wave velocity, m/s

11.10 (9.88, 12.62)

11.03 (9.85, 12.54)

11.86 (10.57, 13.37)

CAC score (EBT)

48.74 (3.61, 227.69)

32.50 (3.09, 182.38)

322.60 (79.30, 819.52)

Absent, mild, moderate, severe EBT-CAC scores (n)

73, 201, 101, 80

71, 190, 89, 58

2, 11, 12, 22

CAC score (MDCT)

77.40 (4.95, 363.32)

57.45 (3.18, 294.02)

541.80 (118.00, 1,397.60)

Absent, mild, moderate, severe MDCT-CAC scores (n)

52, 116, 75, 75

52, 107, 69, 56

0, 8, 6, 19

SBP, mmHg

139.08 ± 19.77

139.24 ± 19.90

137.20 ± 18.12

DBP, mmHg

76.45 ± 11.09

76.73 ± 11.09

73.12 ± 10.65

Use of blood pressure lowering medication

1,577 (53)

1,368 (50)

209 (92)

Hypertension

2,166 (72)

1,949 (70)

217 (95)

Presence of carotid plaques

2469 (85.7)

2257 (84.8)

209 (95.9)

Plaque score

2 (1, 4)

2 (1, 4)

4 (3, 5)

SAF, A.U

2.40 ± 0.49

2.38 ± 0.48

2.64 ± 0.52

  1. MI myocardial infarction, MET the metabolic equivalent of task, with one MET defined as 1 kcal/kg/hour, HDL high-density lipoprotein, eGFR estimated glomerular filtration rate, CAC coronary artery calcification, EBCT electron-beam tomography, MDCT multi-detector computed tomography, SBP systolic blood pressure, DBP diastolic blood pressure, SAF skin autofluorescence