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Table 3 Cox hazard regression for the association of glycemic variability with severe consciousness disturbance and in-hospital death

From: Association of glycemic variability with death and severe consciousness disturbance among critically ill patients with cerebrovascular disease: analysis of the MIMIC-IV database

Outcomes

HR Per unit of Log CV

P value

HR Per unit of Log CV

P value

HR Per unit of Log CV

P value

Model 1

 

Model 2

 

Model 3

 

Non-traumatic cerebral hemorrhage

      

GCS < 8

1.864 (1.578–2.201)

< 0.001

1.830 (1.547–2.165)

< 0.001

1.394 (1.143–1.699)

0.001

In-hospital death

1.927 (1.600-2.322)

< 0.001

1.876 (1.552–2.267)

< 0.001

1.812 (1.452–2.260)

< 0.001

Both

1.914 (1.660–2.206)

< 0.001

1.872 (1.622–2.161)

< 0.001

1.560 (1.318–1.845)

< 0.001

Cerebral infarction

      

GCS < 8

1.486 (1.285–1.719)

< 0.001

1.486 (1.285–1.718)

< 0.001

1.215 (1.032–1.432)

0.020

In-hospital death

1.545 (1.316–1.814)

< 0.001

1.500 (1.277–1.760)

< 0.001

1.234 (1.030–1.477)

0.022

Both

1.566 (1.387–1.768)

< 0.001

1.551 (1.374–1.751)

< 0.001

1.275 (1.112–1.462)

< 0.001

  1. Abbreviations: HR, Hazard ratio; GCS, Glasgow coma scale; BMI, body mass index; CAD, coronary artery disease; AF, atrial fibrillation; MV, mechanical ventilation; CRRT, continuous renal replacement therapy
  2. Model 1: unadjusted;
  3. Model 2: adjusted for age, sex, race, and BMI;
  4. Model 3: adjusted for age, sex, race, BMI, CAD, diabetes, heart failure, hypertension, sepsis, AF, MV. CRRT, antidiabetes therapy, antihypertensive therapy, and glucose measurement number