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Table 2 Baseline characteristics of patients with cerebral infarction according to tertiles of glycemic variability

From: Association of glycemic variability with death and severe consciousness disturbance among critically ill patients with cerebrovascular disease: analysis of the MIMIC-IV database

Characteristics

Total patients n = 2967

T1 (< 16.0%)

n = 989

T2 (16.0-24.7%)

n = 989

T3 (> 24.7%)

n = 989

p

Age

73.11 (62.13–82.53)

71.81 (60.25–82.04)

74.11 (63.36–83.06)

73.39 (63.59–82.49)

0.004

BMI

27.06 (23.38–31.33)

27.32 (23.38–31.84)

26.76 (23.44–30.82)

27.06 (23.28–31.45)

0.254

Sex

    

0.666

 Female

1418 (47.8)

463 (46.8)

483 (48.8)

472 (47.7)

 

 Male

1549 (52.2)

526 (53.2)

506 (51.2)

517 (52.3)

 

Race (White)

1923 (64.8)

646 (65.3)

638 (64.5)

639 (64.6)

0.921

Systolic BP

125.05 (112.85–140.58)

130.48 (116.5–144.63)

122.92 (111.89–138.34)

122.84 (110.78–137.01)

< 0.001

Diastolic BP

63.81 (55.78–73.14)

67.29 (58.72–76.28)

62.26 (54.84–72.30)

61.74 (54.75–70.35)

< 0.001

Mean BP

81.14 (73.20–90.64)

84.31 (75.87–94.02)

80.11 (72.39–90.04)

79.09 (71.89–88.00)

< 0.001

Mean temperature

36.85 (36.63–37.12)

36.89 (36.68–37.12)

36.82 (36.61–37.12)

36.83 (36.60–37.13)

< 0.001

Mean glucose

129.61 (112.25–157.43)

119 (105.60–135.45)

131 (115.00–154.08)

144.42 (121.20–187.67)

< 0.001

CAD

    

< 0.001

No

2460 (82.9)

870 (88.0)

809 (81.8)

781 (79.0)

 

Yes

507 (17.1)

119 (12.0)

180 (18.2)

208 (21.0)

 

COPD

    

0.078

No

2781 (93.7)

935 (94.5)

933 (94.3)

913 (92.3)

 

Yes

186 (6.3)

54 (5.5)

56 (5.7)

76 (7.7)

 

Diabetes

    

< 0.001

No

1916 (64.6)

769 (77.8)

669 (67.6)

478 (48.3)

 

Yes

1051 (35.4)

220 (22.2)

320 (32.4)

511 (51.7)

 

Heart failure

    

< 0.001

No

2169 (73.1)

820 (82.9)

702 (71.0)

647 (65.4)

 

Yes

798 (26.9)

169 (17.1)

287 (29.0)

342 (34.6)

 

Hypertension

    

0.002

No

1354 (45.6)

406 (41.1)

475 (48.0)

473 (47.8)

 

Yes

1613 (54.4)

583 (58.9)

514 (52.0)

516 (52.2)

 

Sepsis

    

< 0.001

No

2645 (89.1)

928 (93.8)

889 (89.9)

828 (83.7)

 

Yes

322 (10.9)

61 (6.2)

100 (10.1)

161 (16.3)

 

Atrial fibrillation

    

0.006

No

1812 (61.1)

640 (64.7)

571 (57.7)

601 (60.8)

 

Yes

1155 (38.9)

349 (35.3)

418 (42.3)

388 (39.2)

 

SOFA

4 (2–6)

3 (2–5)

4 (2–6)

4 (3–7)

< 0.001

APSIII

39 (29–52)

34 (26–44)

39 (29–52)

45 (33–60)

< 0.001

SAPSII

35 (28–43)

31 (25–39)

35 (29–42)

38 (30–47)

< 0.001

OASIS

31 (26–37)

30 (25–35)

32 (26–38)

32 (27–39)

< 0.001

CCI

7 (5–8)

6 (4–8)

7 (5–8)

7 (5–9)

< 0.001

WBC

9.7 (7.45–13)

9.4 (7.3–12.2)

10.1 (7.7–13.2)

9.9 (7.5–13.6)

0.001

RBC

3.67 (3.13–4.22)

3.87 (3.29–4.37)

3.63 (3.12–4.16)

3.54 (2.99–4.11)

< 0.001

Platelet

211 (158–280)

213 (165.5–273)

209 (158–280)

210 (149–286.5)

0.597

PT

13.1 (11.9–14.8)

12.7 (11.7–14.2)

13.1 (11.9–14.8)

13.4 (12.1–15.2)

< 0.001

PTT

29.8 (26.7–36)

29.3 (26.5–34.9)

29.95 (26.8–35)

30.1 (26.8–38)

0.068

Creatine

0.9 (0.7–1.3)

0.9 (0.7–1.1)

0.9 (0.7–1.3)

1 (0.7–1.4)

< 0.001

Sodium

140 (137–142)

140 (137–142)

139 (137–142)

140 (137–142)

0.151

Potassium

4 (3.7–4.4)

4 (3.7–4.3)

4 (3.8–4.4)

4.1 (3.8–4.5)

0.002

Hemoglobin

10.9 (9.3–12.6)

11.5 (9.8–13.1)

10.8 (9.4–12.5)

10.6 (8.9–12.2)

< 0.001

MCH

30.1 (28.7–31.4)

30.15 (28.8–31.4)

30.3 (28.8–31.6)

29.9 (28.5–31.2)

0.004

MCHC

32.9 (31.9–33.8)

33 (32.0–34.0)

33 (32.0–33.9)

32.8 (31.7–33.7)

< 0.001

MCV

91 (87–95)

91 (87–95)

91 (88–95)

91 (87–95)

0.209

Antidiabetes therapy

2353 (79.3)

697 (70.5)

811 (82.0)

845 (85.4)

< 0.001

Antihypertensive therapy

2405 (81.1)

745 (75.3)

840 (84.9)

820 (82.9)

< 0.001

MV

1230 (41.5)

316 (32.0)

447 (45.2)

467 (47.2)

< 0.001

CRRT

85 (2.9)

18 (1.8)

27 (2.7)

40 (4.0)

0.012

Hospital LOS

8.94 (5.67–15.5)

7.58 (4.95–12)

9.69 (6.06–16.65)

10.48 (6.09–17.16)

< 0.001

ICU LOS

3.08 (1.69–6.28)

2.71 (1.51–5.4)

3.19 (1.84–6.73)

3.3 (1.71–6.97)

< 0.001

  1. Abbreviations: BMI, body mass index; BP, blood pressure; CAD, coronary artery disease; COPD, chronic obstructive pulmonary disease; AF, atrial fibrillation; SOFA, Sequential Organ Failure Assessment Score; OASIS, Oxford Acute Severity of Illness Score; SAPSII, Simplified Acute Physiology Score; CCI, Charlson comorbidity index; WBC, white blood cell; RBC, red blood cell; PT, prothrombin time; PTT, active partial thromboplastin time; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; MCV, Mean Corpuscular Volume; MV, mechanical ventilation; CRRT, continuous renal replacement therapy; LOS, length of stay; ICU, intensive care unit