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Table 1 Baseline characteristics of patients with non-traumatic cerebral hemorrhage according to tertiles of glycemic variability

From: Association of glycemic variability with death and severe consciousness disturbance among critically ill patients with cerebrovascular disease: analysis of the MIMIC-IV database

Characteristics

Total patients n = 1842

T1 (< 14.1%)

n = 614

T2 (14.1–21.5%)

n = 614

T3 (> 21.5%)

n = 614

p

Age

67.72 (55.54–79.24)

67.14 (54.51–79.71)

67.23 (54.57–78.88)

68.24 (58.09–78.82)

0.240

BMI

26.57 (23.03–30.9)

26.57 (22.89–30.85)

27.28 (23.5–31.52)

26.21 (22.87–30.46)

0.158

Sex

    

0.685

 Female

824 (44.7)

278 (45.3)

266 (43.3)

280 (45.6)

 

 Male

1018 (55.3)

336 (54.7)

348 (56.7)

334 (54.4)

 

Race (White)

1158 (62.9)

398 (64.8)

389 (63.3)

371 (60.4)

0.268

Systolic BP

128.47 (119–136.79)

129.44 (120.73–137.18)

128.71 (119.26–136.93)

127.07 (116.68–135.36)

0.012

Diastolic BP

65.33 (58.75–72.91)

66.47 (60.36–73.94)

65.52 (58.66–73.29)

63.84 (57.27–71.53)

< 0.001

Mean BP

83.16 (76.25–90.07)

84.16 (77.8–90.71)

83.55 (76.77–90.3)

81.75 (74.88–88.26)

< 0.001

Mean temperature

36.94 (36.7–37.25)

36.97 (36.74–37.25)

36.95 (36.73–37.28)

36.89 (36.65–37.24)

0.023

Mean glucose

128.78 (110.67–152.26)

119.67 (107.17–136.5)

126.67 (110–145.29)

147.88 (120.79–185.46)

< 0.001

CAD

    

< 0.001

No

1774 (96.3)

606 (98.6)

594 (96.7)

574 (93.5)

 

Yes

68 (3.7)

8 (1.4)

20 (3.3)

40 (6.5)

 

COPD

    

0.987

No

1760 (95.5)

586 (95.4)

587 (95.6)

587 (95.6)

 

Yes

82 (4.5)

28 (4.6)

27 (4.4)

27 (4.4)

 

Diabetes

    

< 0.001

No

1464 (79.5)

549 (89.4)

521 (84.9)

394 (64.2)

 

Yes

378 (20.5)

65 (10.6)

93 (15.1)

220 (35.8)

 

Heart failure

    

< 0.001

No

1665 (90.4)

571 (93.0)

561 (91.4)

533 (86.8)

 

Yes

177 (9.6)

43 (7.0)

53 (8.6)

81 (13.2)

 

Hypertension

    

0.249

No

775 (42.1)

250 (40.7)

250 (40.7)

275 (44.8)

 

Yes

1067 (57.9)

364 (59.3)

364 (59.3)

339 (55.2)

 

Sepsis

    

< 0.001

No

1730 (93.9)

602 (98.0)

580 (94.5)

548 (89.3)

 

Yes

112 (6.1)

12 (2.0)

34 (5.5)

66 (10.7)

 

AF

    

0.169

No

1475 (80.1)

489 (79.6)

506 (82.4)

480 (78.2)

 

Yes

367 (19.9)

125 (20.4)

108 (17.6)

134 (21.8)

 

SOFA

3 (2–5)

2 (1–4)

3 (2–4)

4 (2–6)

< 0.001

APSIII

34 (26–45)

30 (23–39)

33 (25–44)

40 (30–55.75)

< 0.001

SAPSII

32 (24–40)

29 (22–37)

31 (24–39)

36 (27–46)

< 0.001

OASIS

30 (24.25–36)

28 (23–33)

30 (25–36)

32 (26–38)

< 0.001

CCI

5 (3–7)

5 (3–6)

5 (3–7)

6 (4–8)

< 0.001

WBC

9.7 (7.4–12.6)

9.4 (7.6–11.7)

9.6 (7.4–12.3)

10.2 (7.3–14)

0.001

RBC

3.9 (3.36–4.39)

4.04 (3.57–4.44)

3.89 (3.33–4.4)

3.78 (3.22–4.3)

< 0.001

Platelet

214 (167–274)

212 (169.5–261.5)

222 (174–286)

206 (150.25–276.75)

0.001

PT

12.5 (11.6–13.6)

12.3 (11.5–13.2)

12.3 (11.5–13.5)

12.9 (11.8–14.3)

< 0.001

PTT

28.3 (25.8–31.5)

28.35 (25.7–31.1)

27.9 (25.9–30.78)

28.7 (25.8–32.2)

0.037

Creatine

0.8 (0.6–1.1)

0.8 (0.6–1)

0.8 (0.6–1)

0.9 (0.7–1.2)

< 0.001

Sodium

139 (137–142)

139 (137–142)

140 (137–142)

139 (137–142)

0.724

Potassium

3.9 (3.6–4.2)

3.9 (3.6–4.2)

3.9 (3.7–4.2)

3.9 (3.6–4.3)

0.882

Hemoglobin

11.9 (10.2–13.2)

12.4 (10.8–13.5)

11.8 (10.2–13.2)

11.4 (9.8–12.9)

< 0.001

MCH

30.5 (29.1–31.8)

30.6 (29.2–32)

30.5 (29.1–31.8)

30.5 (29.05–31.75)

0.192

MCHC

33.3 (32.4–34.3)

33.4 (32.5–34.42)

33.3 (32.3–34.3)

33.4 (32.3–34.3)

0.103

MCV

91 (87–95)

91 (88–95)

91 (87–95)

91 (87–95)

0.822

Antidiabetes therapy

1427 (77.5)

416 (67.8)

475 (77.4)

536 (87.3)

< 0.001

Antihypertensive therapy

1523 (82.7)

496 (80.8)

533 (86.8)

494 (80.5)

0.004

MV

716 (38.9)

165 (26.9)

250 (40.7)

301 (49.0)

< 0.001

CRRT

33 (1.8)

2 (0.3)

6 (0.9)

25 (4.1)

< 0.001

Hospital LOS

9.07 (5.49–15.41)

7.24 (4.82–11.67)

10.66 (6.79–17.74)

10.02 (5.25–17.9)

< 0.001

ICU LOS

3.78 (1.92–7.76)

3.28 (1.74–6.57)

4.61 (2.19–9.18)

3.75 (1.93–7.68)

< 0.001

  1. Abbreviations: BMI, body mass index; BP, blood pressure; CAD, coronary artery disease; COPD, chronic obstructive pulmonary disease; AF, atrial fibrillation; SOFA, Sequential Organ Failure Assessment Score; OASIS, Oxford Acute Severity of Illness Score; SAPSII, Simplified Acute Physiology Score; CCI, Charlson comorbidity index; WBC, white blood cell; RBC, red blood cell; PT, prothrombin time; PTT, active partial thromboplastin time; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; MCV, Mean Corpuscular Volume; MV, mechanical ventilation; CRRT, continuous renal replacement therapy; LOS, length of stay; ICU, intensive care unit