Table 1 Baseline characteristics of participants by cumulative AIP quartile

N

54,123

13,530

13,531

13,531

13,531

-

Age, years

49.05 ± 11.84

49.35 ± 12.41

49.38 ± 12.11

49.08 ± 11.71

48.41 ± 11.05

< 0.01

Male, N(%)

41,303(76.3)

9269.0(68.5)

10,047(74.3)

10,721(79.2)

11,266(83.3)

< 0.01

SBP, mmHg

129.39 ± 16.83

125.33 ± 17.16

128.67 ± 16.87

130.62 ± 16.19

132.94 ± 16.14

< 0.01

DBP, mmHg

83.52 ± 9.20

80.75 ± 9.08

82.89 ± 9.07

84.36 ± 8.76

86.07 ± 9.02

< 0.01

BMI, kg/m²

25.02 ± 3.16

23.38 ± 2.89

24.66 ± 2.99

25.53 ± 2.96

26.51 ± 2.96

< 0.01

HDL-C, mmol/L

1.54 ± 0.32

1.76 ± 0.36

1.57 ± 0.27

1.47 ± 0.24

1.36 ± 0.26

< 0.01

LDL-C, mmol/L

2.50 ± 0.64

2.34 ± 0.65

2.54 ± 0.62

2.59 ± 0.60

2.52 ± 0.64

< 0.01

FPG, mmol/L

5.54 ± 1.38

5.26 ± 1.12

5.46 ± 1.26

5.60 ± 1.38

5.86 ± 1.65

< 0.01

eGFR, ml/min/1.73m²

87.41 ± 17.55

89.62 ± 16.97

87.33 ± 17.48

85.66 ± 17.56

87.03 ± 17.94

< 0.01

TC, mmol/L

4.97 ± 0.85

4.82 ± 0.81

4.93 ± 0.81

4.99 ± 0.84

5.14 ± 0.92

< 0.01

TG,mmol/L

1.67 ± 1.15

0.82 ± 0.22

1.20 ± 0.27

1.63 ± 0.40

3.02 ± 1.48

< 0.01

hs-crp, mg/L

2.59 ± 3.60

2.38 ± 3.71

2.59 ± 3.76

2.56 ± 3.51

2.83 ± 3.40

< 0.01

AIP index₂₀₀₆

-0.10 ± 0.68

-0.75 ± 0.42

-0.31 ± 0.39

0.05 ± 0.44

0.60 ± 0.57

< 0.01

AIP index₂₀₀₈

-0.08 ± 0.69

-0.86 ± 0.35

-0.30 ± 0.28

0.07 ± 0.28

0.76 ± 0.53

< 0.01

AIP index₂₀₁₀

-0.10 ± 0.73

-0.81 ± 0.46

-0.29 ± 0.41

0.05 ± 0.43

0.67 ± 0.63

< 0.01

cumAIP

-0.09 ± 0.60

-0.82 ± 0.24

-0.30 ± 0.11

0.06 ± 0.11

0.70 ± 0.38

< 0.01

Current smoker, N(%)

20,735(38.3)

4382.0(32.4)

4877.0(36.0)

5272.0(39.0)

6204.0(45.9)

< 0.01

Current drinker, N(%)

19,200(35.5)

4283.0(31.7)

4403.0(32.5)

4738.0(35.0)

5776.0(42.7)

< 0.01

Physical activity, N(%)

7764.0(14.3)

1996.0(14.8)

1993.0(14.7)

1904.0(14.1)

1871.0(13.8)

0.07

High school or above, N(%)

15,076(27.9)

3595.0(26.6)

3720.0(27.5)

3826.0(28.3)

3935.0(29.1)

< 0.01

Hypertension, N(%)

25,861(47.8)

5035.0(37.2)

6081.0(44.9)

6889.0(50.9)

7856.0(58.1)

< 0.01

Diabetes mellitus, N(%)

6012.0(11.1)

814.00(6.02)

1190.0(8.79)

1595.0(11.8)

2413.0(17.8)

< 0.01

Hypoglycemic drugs, N(%)

3123.0(5.77)

459.00(3.39)

657.00(4.86)

822.00(6.07)

1185.0(8.76)

< 0.01

Anti-hypertensive drugs, N(%)

8395.0(15.5)

1358.0(10.0)

1837.0(13.6)

2368.0(17.5)

2832.0(20.9)

< 0.01

Lipid-lowering drugs, N(%)

1481.0(2.74)

158.00(1.17)

278.00(2.05)

358.00(2.65)

687.00(5.08)

< 0.01