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Table 2 Comparison of baseline characteristics between the control and T2D groups

From: Cardioprotective function of sclerostin by reducing calcium deposition, proliferation, and apoptosis in human vascular smooth muscle cells

Baseline Characteristics

Control

T2D

p

Men/women (n)

61/53

78/61

0.989

Age (years)

65 ± 9

65 ± 8

0.267

Body weight (kg)

74.9 ± 14.6

86.2 ± 14.4

< 0.001*

Height (cm)

163 ± 0.1

164 ± 0.09

0.298

BMI (kg/m2)

28 ± 4.8

31.8 ± 4.6

< 0.001*

Waist circumference (cm)

97 ± 10.7

105.9 ± 10.8

< 0.001*

FPG (mg/dL)

91 (84–99)

143 (107–173)

< 0.001*

HbA1c (%)

5.6 (5.4–5.8)

7.6 (6.9–8.6)

< 0.001*

TG (mg/dL)

103 (78–144)

139 (99–197)

< 0.001*

HDL-c (mg/dL)

54 ± 12

46 ± 11

< 0.001*

LDL-c (mg/dL)

116 ± 32

93 ± 40

< 0.001*

eGFR (mL/min/1.73 m2)

86.3 (73.5–94)

87 (71.1–97.5)

0.568

Calcium (mg/dL)

9.7 (9.5–10.1)

9.7 (9.5–9.9)

0.553

Phosphorous (mg/dL)

3.2 (2.9–3.5)

3.3 (2.9–3.6)

0.169

25(OH)D (ng/mL)

25.6 ± 8.5

20.7 ± 8.5

< 0.001*

P1NP (ng/mL)

43.8 ± 21

37.2 ± 15

0.002*

ALP (µg/L)

12.6 (10.3–16.9)

16.6 (13.3–21.4)

< 0.001*

iPTH (pg/mL)

52 (40.1–69.3)

46.8 (31.25-61)

0.007*

OC (ng/mL)

21.7 ± 17.4

10.8 ± 5.6

< 0.001*

Periostin (pmol/L)

1208.8 (972–1452)

1147 (936–1546)

0.975

Sclerostin (pmol/L)

32.6 (24.82–43.14)

39.02 (28.20-49.47)

0.003*

  1. T2D, type 2 diabetes; BMI, body mass index; FPG, fasting plasma glucose; HbA1c, glycated haemoglobin; TG, triglycerides; HDL-c, high-density lipoprotein cholesterol; LDL-c, low density lipoprotein cholesterol; eGFR, estimated glomerular filtration rate; 25(OH)D, 25-hydroxyvitamin D; P1NP, procollagen type 1 N-terminal propeptide; ALP, alkaline phosphatase; iPTH, intact parathormone; OC, osteocalcin. Data for continuous and normally distributed variables are presented as mean ± standard deviation. Data for continuous variables not normally distributed, are presented as median followed by interquartile range in brackets. Data for categorical variables are presented as percentages. Student´s t-test and Mann-Whitney U test were used for comparisons of continuous and normally or not normally distributed variables, respectively, between groups. χ2 test was used for comparison of categorical variables between groups. * = p < 0.05 between groups