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Table 4 Univariable and multivariable linear regression analysis of LV global peak strain in RCM patients

From: Effects of diabetes mellitus on left ventricular function and deformation in patients with restrictive cardiomyopathies: a 3.0T CMR feature tracking study

 

GRPS

GCPS

GLPS

Univariable

Multivariable

Univariable

Multivariable

Univariable

Multivariable

r

p value

β

p value

r

p value

β

p value

r

p value

β

p value

Age#, years

0.042

0.573

  

0.033

0.659

  

− 0.036

0.626

  

Male, n (%)

0.057

0.446

  

− 0.092

0.216

  

− 0.008

0.918

  

BMI, kg/m2

0.058

0.434

  

− 0.081

0.277

  

− 0.122

0.101

  

NYHA

− 0.251

0.001

  

0.262

 < 0.001

  

0.280

 < 0.001

  

Hyperlipidemia

0.044

0.554

  

− 0.004

0.961

  

− 0.073

0.327

  

Hypertension

− 0.053

0.473

  

0.057

0.442

  

0.086

0.249

  

DM

− 0.205

0.005

− 0.217

 < 0.001

0.153

0.039

0.176

0.005

0.237

0.001

0.253

 < 0.001

eGFR, mL/min/1.73m2

0.106

0.192

  

− 0.077

0.340

  

− 0.085

0.295

  

NT-proBNPa

− 0.418

 < 0.001

− 0.181

0.007

0.482

 < 0.001

0.299

 < 0.001

0.451

 < 0.001

0.249

 < 0.001

LGE type

− 0.424

 < 0.001

− 0.379

 < 0.001

0.384

 < 0.001

0.280

 < 0.001

0.393

 < 0.001

0.320

 < 0.001

LVMI, g/m2

− 0.381

 < 0.001

− 0.269

 < 0.001

0.348

 < 0.001

0.209

0.001

0.305

 < 0.001

0.177

0.007

  1. DM diabetes mellitus, RCM restrictive cardiomyopathy, BMI body mass index, BP blood pressure, NYHA New York Heart Association, HbA1c glycated hemoglobin,; eGFR estimated glomerular filtration rate, LVEDVi left ventricular end diastolic volume index, LVESVi left ventricular end systolic volume index, LVSVi left ventricular stroke volume index, LVEF left ventricular ejection fraction, LVMI left ventricular mass index, LVGFI left ventricular global function index, GPS global peak strain, PSSR peak systolic strain rate, PDSR peak diastolic strain rate, LGE late gadolinium enhancement
  2. aNT-proBNP was log-transformed before being included in the regression analysis