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Table 1 Baseline characteristics of the study cohort

From: Effects of diabetes mellitus on left ventricular function and deformation in patients with restrictive cardiomyopathies: a 3.0T CMR feature tracking study

 

Control subjects (n = 66)

RCM(DM−) (n = 136)

RCM (DM+) (n = 46)

Baseline characteristics

 Age, years

57.42 ± 8.65

58.35 ± 10.76

58.46 ± 11.97

 Male, n (%)

45(68.18%)

83(61.03%)

27(58.70%)

 BMI, kg/m2

23.31(21.78,25.27)

22.15 ± 2.95

22.04 ± 3.00

 Systolic BP, mmHg

127.83 ± 16.19

100.84 ± 22.41

110.26 ± 26.51

 Diastolic BP, mmHg

76.58 ± 10.16

77.50(68.00–90.00)

80.50(71.00–90.50)

 Heart rate, bpm

73.74(65.25,78.97)

85.54(76.73,95.38)*

91.44(80.26,103.03)*

Cardiac amyloidosis, n (%)

 

114(83.8%)

42(91.3%)

Cardiac risk factors, n (%)

 Hypertension

–

40(29.41%)

25(54.35%)§

 Hyperlipidemia

–

11(8.09%)

5(10.87%)

 Atrial fibrillation

–

15(11.0%)

4(8.69%)

NYHA functional class, n

 I/II/III/IV

–

6(4.41%)/51(37.50%)/58(42.65%)/21(15.44%)

1(2.17%)/6(13.04%)/27(58.70%)/12(26.09%)§

Laboratory data

 HbA1c, %

–

–

7.40(6.80,8.00)

 eGFR, mL/min/1.73m2

–

79.94 ± 28.45

71.91 ± 33.67

 Creatinine, umol/L

–

78.00(58.00,102.50)

81.00(69.50,126.25)

 Troponin, ng/L

–

78.55(39.85,138.80)

92.40(45.25,149.15)

 NT-proBNP

–

4322.50(1436.00–7777.75)

7642.00(1337.00–13602.00)§

  1. DM diabetes mellitus, RCM restrictive cardiomyopathy, BMI body mass index, BP blood pressure, NYHA New York Heart Association, HbA1c glycated hemoglobin, eGFR estimated glomerular filtration rate
  2. *p < 0.05 versus control group (Bonferroni’s)
  3. §p < 0.05 versus RCM patients without DM