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Fig. 1 | Cardiovascular Diabetology

Fig. 1

From: Direct regulation of the cardiac ryanodine receptor (RyR2) by O-GlcNAcylation

Fig. 1

RyR2 is O-GlcNAcylated. (A) Representative blots showing total O-GlcNAc-RyR2 and total RyR2 expression from diabetic and non-diabetic human right atrial appendages (RAA) and left ventricles of Zucker diabetic fatty (ZDF) rat and non-diabetic lean (control) rats. The samples are labelled above the corresponding lane. O-GlcNAc modified RyR2 normalised to total RyR2 expression in (B) human RAA samples (n = 8 per group) and, (C) rat LV samples (n = 9 per group). Data displayed as Mean ± SEM. Statistical analysis was performed using a Welch’s t test

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