Fig. 2
From: Diabetes- versus smoking-related thrombo-inflammation in peripheral artery disease
Hypothetical image of the increasingly thrombo-inflammatory processes behind the course of peripheral artery disease in diabetes mellitus compared with cigarette smoking. DM: diabetes mellitus. NO: nitric oxide. ROS: reactive oxygen species. TF: tissue factor. TNF-α: tumor necrosis factor-α. PAI-1: plasminogen activator inhibitor-1. TAFI: thrombin activatable fibrinolysis inhibitor