Microvesicle-associated and circulating microRNAs in diabetic dyslipidemia: miR-218, miR-132, miR-143, and miR-21, miR-122, miR-155 have biomarker potential

Table 2 Significant correlations among circulating/plasma inflammatory cytokines and relevant clinical parameters in the diabetic dyslipidemia context

T₂D-DLP group		Cytokine plasma levels
T₂D-DLP group		IFNγ	TNFα	IL1β	IL6
Clinical measurements ↓	n	17	17	17	17
TC	r	− 0.610	− 0.184	− 0.324	− 0.013
TC	P	0.264	0.763	0.593	0.974
HDL-c	r	0.531	0.461	0.162	− 0.312
HDL-c	P	0.351	0.423	0.783	0.604
LDL-c	r	0.504	0.123	− 0.594	0.293
LDL-c	P	0.390	0.843	0.297	0.624
TG	r	− 0.583	− 0.612	0.053	0.594
TG	P	0.293	0.261	0.924	0.292
TGO	r	− 0.452	− 0.581	0.082	0.711
TGO	P	0.432	0.302	0.894	0.170
TGP	r	0.821	0.120	− 0.443	0.563
TGP	P	0.080	0.843	0.453	0.322
Fasting Glucose	r	0.502	0.284	− 0.453	− 0.573
Fasting Glucose	P	0.383	0.643	0.434	0.314
HbA1c	r	0.573	− 0.411	0.413	0.073
HbA1c	P	0.311	0.484	0.492	0.903
Hemoglobin	r	0.083	− 0.453	0.256	0.784
Hemoglobin	P	0.894	0.433	0.673	0.103
Creatinine	r	− 0.024	− 0.132	− 0.253	0.754
Creatinine	P	0.964	0.822	0.684	0.133
Urea	r	− 0.373	− 0.351	− 0.273	0.711
Urea	P	0.532	0.553	0.652	0.174
Uric acid	r	− 0.674	− 0.684	0.253	0.201
Uric acid	P	0.213	0.203	0.681	0.743
Erythrocytes	r	− 0.504	− 0.633	0.150	0.184
Erythrocytes	P	0.392	0.252	0.804	0.773
Platelets	r	0.334	0.811	− 0.624	− 0.590
Platelets	P	0.581	0.094	0.250	0.293
Leucocytes	r	0.881	0.260	− 0.171	0.371
Leucocytes	P	0.040	0.664	0.770	0.532
Monocytes	r	− 0.752	0.093	0.314	− 0.773
Monocytes	P	0.144	0.884	0.604	0.123
SBP (systolic blood pressure)	r	0.224	− 0.783	0.900	0.182
SBP (systolic blood pressure)	P	0.713	0.113	0.031	0.750
DBP (diastolic blood pressure)	r	− 0.074	− 0.022	0.303	0.660
DBP (diastolic blood pressure)	P	0.893	0.961	0.624	0.211

Spearman rank correlation test was used to assess relationships among variables. Bolded coefficients show a powerful correlation, and of them only italic underlined coefficients are significant (p < 0.05)

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