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Table 3 Associations of different classes of change in TyG-BMI with stroke incidence stratified by different factors

From: Changes in the triglyceride glucose-body mass index estimate the risk of stroke in middle-aged and older Chinese adults: a nationwide prospective cohort study

Subgroup

Change in the TyG-BMI, OR (95% CI)

P for interaction

Class 1 (n = 1273)

Class 2 (n = 1664)

Class 3 (n = 1171)

Class 4 (n = 475)

Age (years)

    

0.192

 < 60

Reference

1.22 (0.59–2.54)

2.07 (1.09–3.93)

2.65 (1.18–5.92)

 

 ≥ 60

Reference

0.92 (0.52–1.64)

1.45 (0.91–2.28)

1.16 (0.54–2.51)

 

Sex

    

0.919

 Male

Reference

1.16 (0.60–2.25)

1.54 (0.92–2.59)

1.83 (0.78–4.30)

 

 Female

Reference

0.88 (0.47–1.62)

1.60 (0.93–2.73)

1.63 (0.82–3.25)

 

Marital status

    

0.122

 Married

Reference

1.25 (0.74–2.09)

1.95 (1.25–3.04)

1.90 (1.04–3.45)

 

 Other

Reference

0.49 (0.18–1.33)

1.08 (0.53–2.17)

1.45 (0.41–5.19)

 

Residence

    

0.319

 Urban

Reference

0.93 (0.34–2.59)

2.49 (0.99–6.26)

1.79 (0.58–5.50)

 

 Rural

Reference

1.07 (0.65–1.78)

1.42 (0.94–2.14)

1.60 (0.86–2.98)

 

Educational level

    

0.153

 No formal education

Reference

0.80 (0.37–1.73)

1.15 (0.63–2.10)

1.35 (0.53–3.43)

 

 Primary school

Reference

1.03 (0.53–2.02)

1.84 (1.06–3.20)

1.57 (0.68–3.59)

 

 Middle or high school

Reference

2.50 (0.75–8.31)

3.64 (1.19–11.16)

4.46 (1.19–16.69)

 

 College or above

Reference

NA

NA

NA

 

Smoking status

    

0.999

 Never

Reference

0.91 (0.51–1.65)

1.59 (0.95–2.66)

1.62 (0.82–3.19)

 

 Former

Reference

0.95 (0.24–3.75)

1.29 (0.42–4.00)

2.16 (0.43–10.78)

 

 Current

Reference

1.29 (0.55–3.00)

1.60 (0.85–2.99)

1.88 (0.64–5.50)

 

Drinking status

    

0.860

 Never

Reference

0.99 (0.56–1.77)

1.48 (0.90–2.44)

1.42 (0.72–2.83)

 

 Former

Reference

0.52 (0.12–2.21)

1.23 (0.39–3.88)

0.76 (0.11–5.52)

 

 Current

Reference

1.12 (0.49–2.57)

1.87 (0.98–3.58)

2.46 (0.92–6.56)

 

Hypertension

    

0.540

 No

Reference

1.03 (0.58–1.83)

1.49 (0.97–2.29)

2.06 (1.00–4.27)

 

 Yes

Reference

1.20 (0.53–2.74)

2.24 (1.04–4.83)

1.78 (0.72–4.39)

 

Diabetes

    

0.556

 No

Reference

1.01 (0.64–1.59)

1.65 (1.14–2.39)

1.73 (0.99–3.02)

 

 Yes

Reference

0.75 (0.06–9.83)

0.72 (0.06–9.34)

1.09 (0.07–15.94)

 

Heart disease

    

0.752

 No

Reference

0.96 (0.59–1.56)

1.50 (1.02–2.23)

1.74 (0.98–3.10)

 

 Yes

Reference

1.12 (0.34–3.75)

2.23 (0.76–6.60)

1.67 (0.43–6.44)

 

Dyslipidaemia

    

0.529

 No

Reference

0.91 (0.57–1.46)

1.54 (1.05–2.25)

1.79 (1.00–3.22)

 

 Yes

Reference

2.68 (0.31–23.49)

3.99 (0.47–33.50)

3.73 (0.40–34.69)

 

Kidney disease

    

0.865

 No

Reference

0.94 (0.60–1.49)

1.55 (1.06–2.26)

1.68 (0.98–2.88)

 

 Yes

Reference

2.20 (0.31–15.64)

3.22 (0.49–21.26)

3.22 (0.24–43.38)

 
  1. BMI: body mass index; CI: confidence interval; OR: odds ratio; TyG: triglyceride-glucose; NA: not applicable
  2. All models were adjusted for age, sex, marital status, residence, educational level, smoking status, drinking status, history of hypertension, diabetes, heart disease, dyslipidaemia, kidney disease, medication use for hypertension, medication use for diabetes, medication use for dyslipidaemia, systolic blood pressure, diastolic blood pressure, total cholesterol, HDL-C, LDL-C, HbA1c, and the eGFR
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Cardiovascular Diabetology

ISSN: 1475-2840