Skip to main content

Table 1 Baseline characteristics of 4583 participants according to the change in the TyG-BMI

From: Changes in the triglyceride glucose-body mass index estimate the risk of stroke in middle-aged and older Chinese adults: a nationwide prospective cohort study

Characteristic

Overall (n = 4583)

Change in the TyG-BMI

P valuea

Class 1 (n = 1273)

Class 2 (n = 1664)

Class 3 (n = 1171)

Class 4 (n = 475)

Age, mean ± SD, years

58.68 ± 8.62

60.97 ± 8.94

58.50 ± 8.47

57.30 ± 8.26

56.55 ± 7.72

< 0.001

Sex

     

< 0.001

 Male

2056 (44.9%)

743 (58.4%)

733 (44.1%)

424 (36.2%)

156 (32.8%)

 

 Female

2527 (55.1%)

530 (41.6%)

931 (55.9%)

747 (63.8%)

319 (67.2%)

 

Marital status

     

< 0.001

 Married

3905 (85.2%)

1052 (82.6%)

1407 (84.6%)

1012 (86.4%)

434 (91.4%)

 

 Other

678 (14.8%)

221 (17.4%)

257 (15.4%)

159 (13.6%)

41 (8.6%)

 

Residence

     

< 0.001

 Urban

1528 (33.3%)

301 (23.6%)

537 (32.3%)

481 (41.1%)

209 (44.0%)

 

 Rural

3055 (66.7%)

972 (76.4%)

1127 (67.7%)

690 (58.9%)

266 (56.0%)

 

Educational level

     

< 0.001

 No formal education

1344 (29.3%)

399 (31.3%)

492 (29.6%)

310 (26.5%)

143 (30.1%)

 

 Primary school

1910 (41.7%)

570 (44.8%)

680 (40.9%)

481 (41.1%)

179 (37.7%)

 

 Middle or high school

1207 (26.3%)

284 (22.3%)

440 (26.4%)

344 (29.4%)

139 (29.3%)

 

 College or above

122 (2.7%)

20 (1.6%)

52 (3.1%)

36 (3.1%)

14 (2.9%)

 

Smoking statusb

     

< 0.001

 Never

2858 (62.4%)

627 (49.3%)

1067 (64.1%)

829 (70.8%)

335 (70.5%)

 

 Former

374 (8.2%)

97 (7.6%)

121 (7.3%)

112 (9.6%)

44 (9.3%)

 

 Current

1341 (29.3%)

546 (42.9%)

471 (28.3%)

228 (19.5%)

96 (20.2%)

 

Drinking statusb

     

< 0.001

 Never

2700 (58.9%)

651 (51.1%)

993 (59.7%)

739 (63.1%)

317 (66.7%)

 

 Former

367 (8.0%)

122 (9.6%)

112 (6.7%)

104 (8.9%)

29 (6.1%)

 

 Current

1513 (33.0%)

499 (39.2%)

558 (33.5%)

327 (27.9%)

129 (27.2%)

 

History of comorbidities

      

 Hypertensionb

1216 (26.5%)

173 (13.6%)

371 (22.3%)

426 (36.4%)

246 (51.8%)

< 0.001

 Diabetesb

281 (6.1%)

26 (2.0%)

74 (4.4%)

103 (8.8%)

78 (16.4%)

< 0.001

 Heart diseaseb

537 (11.7%)

113 (8.9%)

164 (9.9%)

160 (13.7%)

100 (21.1%)

< 0.001

 Dyslipidaemiab

491 (10.7%)

40 (3.1%)

142 (8.5%)

168 (14.3%)

141 (29.7%)

< 0.001

 Kidney diseaseb

256 (5.6%)

70 (5.5%)

84 (5.0%)

75 (6.4%)

27 (5.7%)

0.493

History of medication use

      

 Hypertension medicationsb

885 (19.3%)

114 (9.0%)

249 (15.0%)

318 (27.2%)

204 (42.9%)

< 0.001

 Diabetes medicationsb

171 (3.7%)

18 (1.4%)

38 (2.3%)

61 (5.2%)

54 (11.4%)

< 0.001

 Dyslipidaemia medicationsb

257 (5.6%)

18 (1.4%)

65 (3.9%)

92 (7.9%)

82 (17.3%)

< 0.001

Blood pressure, mean ± SD, mmHg

      

 Systolicb

128.44 ± 20.63

123.79 ± 19.81

127.10 ± 19.89

132.10 ± 20.81

136.61 ± 20.99

< 0.001

 Diastolicb

75.00 ± 11.98

71.39 ± 11.16

74.17 ± 11.53

77.84 ± 11.97

80.64 ± 12.08

< 0.001

TC, mean ± SD, mg/dl

194.74 ± 38.93

185.54 ± 36.22

193.49 ± 37.02

200.13 ± 37.91

210.52 ± 47.15

< 0.001

HDL-C, mean ± SD, mg/dl

51.25 ± 15.29

59.54 ± 16.26

52.23 ± 13.67

45.37 ± 12.09

40.09 ± 11.60

< 0.001

LDL-C, mean ± SD, mg/dlb

117.61 ± 34.97

110.75 ± 31.35

119.58 ± 33.44

122.30 ± 36.10

117.55 ± 43.13

< 0.001

HbA1c, mean ± SD

5.29 ± 0.81

5.14 ± 0.58

5.20 ± 0.65

5.40 ± 0.94

5.73 ± 1.20

< 0.001

eGFR, mean ± SD, ml/min/1.73 m2b

74.51 ± 33.82

73.36 ± 35.30

74.55 ± 32.57

74.89 ± 31.14

76.53 ± 39.88

0.433

TG2012, median (IQR)

104.43 (74.34, 152.22)

74.34 (58.41, 100.00)

100.00 (74.34, 137.18)

135.40 (100.45, 188.51)

193.82 (131.87, 286.30)

< 0.001

TG2015, median (IQR)

113.27 (81.42, 164.60)

80.53 (65.49, 105.31)

107.96 (83.19, 147.79)

150.44 (111.50, 207.08)

208.85 (142.92, 292.92)

< 0.001

FBG2012, mean ± SD

109.61 ± 34.26

102.11 ± 22.68

105.59 ± 24.95

114.56 ± 40.19

131.58 ± 55.19

< 0.001

FBG2015, mean ± SD

101.22 ± 31.66

92.45 ± 18.22

97.44 ± 23.01

107.74 ± 37.91

121.90 ± 51.01

< 0.001

BMI2012, mean ± SD

23.65 ± 3.77

19.79 ± 1.73

23.04 ± 1.62

26.08 ± 2.01

30.14 ± 3.42

< 0.001

BMI2015, mean ± SD

23.81 ± 3.71

19.83 ± 1.76

23.34 ± 1.66

26.37 ± 2.02

29.85 ± 2.96

< 0.001

TyG-BMI2012, mean ± SDc

205.97 ± 40.60

163.42 ± 15.13

197.39 ± 14.40

233.00 ± 17.59

283.42 ± 29.91

< 0.001

TyG-BMI2015, mean ± SDc

207.44 ± 40.06

163.36 ± 15.45

200.17 ± 14.45

236.43 ± 16.93

279.56 ± 27.16

< 0.001

Cumulative TyG-BMI index, mean ± SDd

620.12 ± 115.68

490.18 ± 38.64

596.34 ± 30.55

704.14 ± 34.37

844.48 ± 62.90

< 0.001

  1. BMI: body mass index; eGFR: estimated glomerular filtration ratio; FBG: fast blood glucose; HbA1c: glycated haemoglobin; HDL-C: high-density lipoprotein cholesterol; IQR: interquartile range; LDL-C: low-density lipoprotein cholesterol; SD: standard deviation; TC: total cholesterol; TG: triglyceride; TyG: triglyceride-glucose
  2. aP value was based on χ2 or analysis of variance test where appropriate
  3. bMissing data: 10 for smoking status, 3 for drinking status, 23 for hypertension, 37 for diabetes, 17 for heart disease, 93 for dyslipidaemia, 25 for kidney disease, 23 for hypertension medications, 38 for diabetes medications, 96 for dyslipidaemia medications, 35 for systolic blood pressure, 35 for diastolic blood pressure, 9 for LDL-C, 2 for the eGFR, and 19 for HbA1c
  4. cThe TyG-BMI was calculated by the formula ln[Triglyceride (mg/dl) × Fasting blood glucose (mg/dl)/2] × BMI (kg/m2)
  5. dCumulative TyG-BMI was calculated by the formula (TyG-BMI2012 + TyG-BMI2015)/2 × time(2015−2012)
Back to article page

Cardiovascular Diabetology

ISSN: 1475-2840