Fig. 4

Estimated weights assigned to TyG-BMI with the WQS model. Weights in a positive direction obtained when the effect parameter of the WQS model was constrained to the positive direction with 1 000 repeated holdout validations for TyG-BMI in 2012 (A) and 2015 (B). WQS models were adjusted for age, sex, marital status, residence, educational level, smoking status, drinking status, history of hypertension, diabetes, heart disease, dyslipidaemia, kidney disease, medication use for hypertension, medication use for diabetes, medication use for dyslipidaemia, systolic blood pressure, diastolic blood pressure, total cholesterol, HDL-C, LDL-C, HbA1c, and the eGFR. BMI: body mass index; FBG: fasting blood glucose; TyG: triglyceride-glucose; WQS: weighted quantile sum