Skip to main content

Table 2 Comparison of CMR findings among T2DM patients with/without DPN and normal controls

From: Subclinical left ventricular deformation and microvascular dysfunction in T2DM patients with and without peripheral neuropathy: assessed by 3.0 T cardiac magnetic resonance imaging

 

Controls

T2DM (DPN−)

T2DM (DPN+)

LV geometry

 LVEDV (mL)

123.80 ± 23.27

127.27 ± 26.70

131.81 ± 31.58

 LVEDVI (mL/m2)

72.20 ± 11.53

74.54 ± 14.55

75.77 ± 16.20

 LVESV (mL)

42.96(33.16, 51.85)

45.86 (37.39, 55.16)

43.73 (36.02, 54.63)

 LVESVI (mL/m2)

25.17 (21.27, 29.29)

26.40 (21.67, 31.22)

24.60 (21.68, 30.69)

 LVSV (mL)

79.98 ± 16.19

80.85 ± 17.75

84.13 ± 20.24

 LVSVI (mL/m2)

46.71 ± 8.56

47.29 ± 9.49

48.43 ± 10.38

 Cardiac index (L/min/m2)

3.34 ± 0.86

3.49 ± 0.82

3.59 ± 0.74

 LVEF (%)

64.66 ± 6.38

63.70 ± 7.02

64.12 ± 7.59

 LVM (g)

68.13 (59.61, 82.62)

79.42 (66.53, 95.12)*

90.96 (68.37, 109.01)*

 LVMI (g/m2)

41.25 (37.73, 46.46)

46.81 (38.41, 53.89)*

49.21 (40.73, 59.78)*

 LV remodeling index (g/mL)

0.58 (0.51, 0.64)

0.63 (0.55, 0.74)*

0.66 (0.55, 0.80) *

 Non-infarct LGE, n (%)

NA

22 (17.9)

20 (37.0)&

Myocardial strain

 GRS (%)

36.94 ± 7.21

33.42 ± 7.04*

32.02 ± 9.77*

 GCS (%)

− 21.13 ± 2.53

− 19.99 ± 2.34*

− 19.39 ± 3.25*

 GLS (%)

− 15.07 ± 2.56

− 13.24 ± 2.46*

− 11.92 ± 3.29*&

Myocardial perfusion

 Upslope

2.69 ± 1.19

2.25 ± 1.18*

1.76 ± 0.60*&

 TTM (s)

25.73 ± 9.71

31.57 ± 13.39*

31.68 ± 12.86*

 Max SI

22.83 ± 8.41

19.97 ± 7.81*

16.04 ± 4.88*&

  1. The values are mean ± SD, numbers in the brackets are percentages
  2. T2DM type 2 diabetes mellitus, DPN diabetic peripheral neuropathy, LV left ventricular, EDV end diastolic volume, ESV end systolic volume, SV stroke volume, EF ejection fraction, M mass, I indexed to BSA, LGE late gadolinium enhancement, GRS global radial strain, GCS global circumferential strain, GLS global longitudinal strain, TTM time to maximum signal intensity, Max SI max signal intensity
  3. *p < 0.05 versus controls
  4. &P < 0.05 versus T2DM (DPN−) group