Table 2 Platelet reactivity and prevalence of HPR according to DM and DM severity (total n = 11,714)

PRU (n = 11,714)

213.6 ± 79.1

225.7 ± 77.5

< 0.001

HPR to ADP

32.0%

38.1%

< 0.001

ARU (n = 7,162)

442.1 ± 67.7

448.2 ± 72.3

< 0.001

HPR to arachidonic acid

51.6%

53.7%

0.090

Non-DM

(N = 7,657)

DM without insulin

(N = 3,787)

DM on insulin

(N = 270)

P-value

PRU (n = 11,714)

213.6 ± 79.1

225.3 ± 77.8

230.7 ± 73.2

< 0.001

HPR to ADP

32.0%

37.7%

44.0%

0.001

ARU (n = 7,162)

442.1 ± 67.7

446.7 ± 72.2

462.7 ± 74.0

< 0.001

HPR to arachidonic acid

51.6%

52.8%

63.8%

0.002

HbA1c < 6.5

(N = 2,541)

6.5 ≤ HbA1c ≤ 8.5

(N = 1,192)

HbA1c > 8.5

(N = 362)

P-value

PRU (n = 4,095)

216.1 ± 82.2

226.8 ± 81.6

229.4 ± 81.4

< 0.001

HPR to ADP

34.6%

40.2%

40.3%

0.001

ARU (n = 1,115)

436.4 ± 67.1

439.5 ± 70.6

449.7 ± 72.4

0.187

HPR to arachidonic acid

45.9%

47.1%

54.0%

0.314