Association between the triglyceride glucose (TyG) index and the risk of acute kidney injury in critically ill patients with heart failure: analysis of the MIMIC-IV database

Table 3 Cox proportional hazard ratios (HR) for AKI incidence

Categories	Model 1		Model 2		Model 3
Categories	h (95% CI)	P-value	HR (95% CI)	P-value	HR (95% CI)	P-value
AKI incidence
Continuous variable per 1 unit	1.57 [95% CI 1.34–1.84]	< 0.001	1.58 [95% CI 1.34–1.86]	< 0.001	1.58 [95%CI 1.22–2.04]	0.0006
Quartile^a
Q1(N = 349)	Ref.		Ref.		Ref.
Q2(N = 348)	1.11 [95% CI 0.94–1.31]	0.226	1.10 [95% CI 0.93–1.30]	0.26	1.04 [95% CI 0.88–1.24]	0.655
Q3(N = 348)	1.27 [95% CI1.08–1.50]	0.004	1.24 [95% CI1.06–1.47]	0.009	1.16 [95% CI 0.96–1.39]	0.122
Q4(N = 348)	1.42 [95% CI 1.20–1.67]	<0.001	1.42 [95% CI1.20–1.67]	<0.001	1.32 [95% CI 1.06–1.65]	0.012

Model 1 was unadjusted
Model 2 was adjusted for sex, age, and BMI.
Model 3 was adjusted for the variables in model 2 and further adjusted for race, SBP, DBP, HR, SOFA, SIRS, APSIII, SAPSII, digoxin, beta blocker, ACEI, ARB, ARNI, loop diuretics, WBC, RBC, hemoglobin, neutrophils, lymphocytes, platelets, albumin, BUN, Scr, Ucr, CKMB, PCO2, CRP, TG, LDL-C, HDL-C, NT-proBNP, potassium, sodium, pH, PO2, HbA1c, TnT, AF, AMI, CKD, COPD, dyslipidemia, diabetes, hypertension, PCI and CABG.
^aTyG index quartile Q1: 3.61–4.61; Q2: 4.61–4.82; Q3: 4.82–5.07; Q4: 5.07–7.18

ISSN: 1475-2840