Table 2 Current unmet needs and potential future directions to improve CMR management
From: The cardio-renal-metabolic connection: a review of the evidence
Unmet needs | Future directions |
|---|---|
Novel medications with CMR benefits | • Identification of druggable CMR connectors • Further efficacy and safety data of novel therapies |
Combination therapy strategy | • Better understanding of drug mechanisms of action • Outcomes trials testing combination therapies |
Integrated management of CMR disease | • Multidisciplinary approach |
Risk-stratified personalized care | • Risk score validation for individualized prognostication • Clinical trials in specific populations (women/young/primary prevention) |
Drug prioritization | • Head-to-head drug comparative trials |