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Fig. 3 | Cardiovascular Diabetology

Fig. 3

From: Rationale and design of an investigator-initiated, multicenter, prospective, placebo-controlled, double-blind, randomized trial to evaluate the effects of finerenone on vascular stiffness and cardiorenal biomarkers in type 2 diabetes and chronic kidney disease (FIVE-STAR)

Fig. 3

Graphical abstract of the FIVE-STAR trial. CAVI, cardio ankle vascular index; CKD, chronic kidney disease; eGFR, estimated glomerular filtration rate; HFrEF: heart failure with reduced ejection fraction; LVEF: left ventricular ejection fraction; MR: mineralocorticoid receptor; MRA: mineralocorticoid receptor antagonist; T2D, type 2 diabetes; UACR, urinary albumin-to-creatinine ratio

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