Table 2 Adjusted hazard ratios for study outcomes associated with triglyceride levels in statin-treated patients
Triglyceride level (mmol/L) | Overall | Males | Females | ||||||
|---|---|---|---|---|---|---|---|---|---|
N/events | Incidence rates per 1000 PY (95% CI) | Adjusted HR (95% CI) | N/events | Incidence rates per 1000 PY (95% CI) | Adjusted HR (95% CI) | N/events | Incidence rates per 1000 PY (95% CI) | Adjusted HR (95% CI) | |
Mace | |||||||||
< 1.0 | 4563/322 | 10.2 (9.2–11.4) | 1.0 | 2538/199 | 11.5 (10.0–13.2) | 1.0 | 2025/123 | 8.7 (7.3–10.4) | 1.0 |
1.0–1.9 | 14,124/1,051 | 11.2 (10.5–11.8) | 1.14 (1.00–1.29) | 7196/608 | 12.9 (11.9–13.9) | 1.17 (0.99–1.37) | 6928/443 | 9.4 (8.6–10.3) | 1.09 (0.89–1.34) |
2.0–2.9 | 5445/390 | 11.3 (10.3–12.5) | 1.30 (1.12–1.51) | 2860/208 | 11.5 (10.0–13.2) | 1.18 (0.97–1.44) | 2585/182 | 11.1 (9.6–12.9) | 1.45 (1.15–1.82) |
≥ 3.0 | 2948/194 | 10.6 (9.2–12.2) | 1.44 (1.20–1.73) | 1826/132 | 11.8 (9.9–14.0) | 1.47 (1.17–1.85) | 1122/62 | 8.8 (6.9–11.3) | 1.32 (0.97–1.80) |
Myocardial infarction | |||||||||
< 1.0 | 4563/84 | 2.3 (1.8–2.8) | 1.0 | 2538/61 | 3.0 (2.3–3.8) | 1.0 | 2025/23 | 1.4 (0.9–2.1) | 1.0 |
1.0–1.9 | 14,124/327 | 2.9 (2.6–3.3) | 1.35 (1.06–1.71) | 7196/202 | 3.6 (3.2–4.2) | 1.22 (0.92–1.63) | 6928/125 | 2.3 (1.9–2.7) | 1.66 (1.07–2.60) |
2.0–2.9 | 5445/141 | 3.5 (2.9–4.1) | 1.67 (1.27–2.20) | 2860/84 | 3.9 (3.2–4.9) | 1.39 (1.00–1.95) | 2585/57 | 2.9 (2.3–3.8) | 2.39 (1.46–3.89) |
≥ 3.0 | 2948/74 | 3.4 (2.7–4.3) | 1.75 (1.27–2.42) | 1826/57 | 4.2 (3.3–5.5) | 1.65 (1.13–2.41) | 1122/17 | 2.0 (1.3–3.3) | 1.78 (0.94–3.37) |
Ischemic stroke | |||||||||
< 1.0 | 4563/172 | 4.7 (4.0–5.4) | 1.0 | 2538/99 | 4.9 (4.0–5.9) | 1.0 | 2025/73 | 4.4 (3.5–5.9) | 1.0 |
1.0–1.9 | 14,124/483 | 4.4 (4.0–4.8) | 0.96 (0.81–1.15) | 7196/277 | 5.0 (4.4–5.6) | 1.06 (0.84–1.33) | 6928/206 | 3.8 (3.7–4.3) | 0.83 (0.63–1.09) |
2.0–2.9 | 5445/173 | 4.2 (3.7–4.9) | 1.04 (0.84–1.29) | 2860/93 | 4.3 (3.5–5.3) | 1.04 (0.78–1.39) | 2585/80 | 4.1 (3.3–5.1) | 1.01 (0.73–1.39) |
≥ 3.0 | 2948/88 | 4.0 (3.3–5.0) | 1.13 (0.86–1.47) | 1826/59 | 4.4 (3.4–5.7) | 1.23 (0.87–1.72) | 1122/29 | 3.5 (2.4–5.0) | 0.97 (0.62–1.50) |
Cardiac death | |||||||||
< 1.0 | 4563/134 | 4.1 (3.5–4.9) | 1.0 | 2538/86 | 4.8 (3.9–6.0) | 1.0 | 2025/48 | 3.3 (2.5–4.4) | 1.0 |
1.0–1.9 | 14,124/454 | 4.7 (4.3–5.2) | 1.20 (0.99–1.46) | 7196/254 | 5.2 (4.6–5.9) | 1.17 (0.91–1.49) | 6928/200 | 4.2 (3.6–4.8) | 1.28 (0.94–1.76) |
2.0–2.9 | 5445/161 | 4.6 (3.9–5.3) | 1.37 (1.08–1.72) | 2860/76 | 4.1 (3.3–5.1) | 1.10 (0.80–1.50) | 2585/85 | 5.1 (4.1–6.2) | 1.79 (1.25–2.56) |
≥ 3.0 | 2948/73 | 3.9 (3.1–4.9) | 1.53 (1.14–2.06) | 1826/44 | 3.8 (2.8–5.1) | 1.42 (0.97–2.07) | 1122/29 | 4.1 (2.8–5.9) | 1.72 (1.08–2.76) |