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Table 5 Multivariate analysis of the outcomes in patients with CT-FFR > 0.75

From: Global trans-lesional computed tomography-derived fractional flow reserve gradient is associated with clinical outcomes in diabetic patients with non-obstructive coronary artery disease

Characteristic

MACE

MACCE

Multivariate HR (95% CI)

Wald x²

P value

Multivariate HR (95% CI)

Wald x²

P value

Age (year)

1.00 (0.98–1.02)

0.039

0.84

1.00 (0.98–1.02)

0.116

0.73

Male

0.87 (0.54–1.40)

0.348

0.56

0.93 (0.61–1.41)

0.116

0.73

Hyperlipidemia

1.83 (1.19–2.81)

7.585

0.006

1.51 (1.04–2.19)

4.772

0.03

Current smoking

1.25 (0.76–2.08)

0.764

0.38

1.20 (0.76–1.87)

0.608

0.44

High-risk plaque

3.62 (2.08–6.30)

20.663

< 0.001

3.18 (1.91–5.31)

19.573

< 0.001

Leiden score

1.71 (1.08–2.71)

5.275

0.02

1.68 (1.13–2.52)

6.442

0.01

GΔCT-FFR ≥ 0.20

2.43 (1.45–4.07)

11.299

0.001

2.11 (1.34–3.34)

10.209

0.001

  1. CI confidence interval, CT-FFR coronary computed tomography angiography-derived fractional flow reserve, GΔCT-FFR global ΔCT-FFR (the sum of the trans-lesional CT-FFR gradient in all epicardial vessels), HR hazard ratio, MACE major adverse cardiovascular events, MACCE major adverse cardiovascular and cerebrovascular events