Table 8 multinomial regression analysis of clinical and laboratory variables associated with diabetes and with DFS (diabetic foot syndrome) in comparison to control healthy subjects and of clinical and laboratory variables associated with diabetic foot con comparison to diabetics without DFS

1.0

Intercept

− 7.66

4.90

2.44

1

0.118

RHI score

− 1.69

1.160

2.12

1

0.145

.184

0.019

1.790

HIF1-a

0.027

0.08

0.108

1

0.743

1.028

0.873

1.210

VEGF

0.012

.010

1.48

1

0.223

1.012

0.993

1.032

GREM-1

5.19

2.52

4.25

1

0.039

180.75

1.295

2522433

VEGFC 2578ACC

2.55

1.27

3.99

1

0.046

12.868

1.050

157.65

2.0

Intercept

− 18.08

5.71

10.01

1

0.002

RHI score

3.69

1.36

7.37

1

0.007

40.34

2.800

581.24

HIF1-a

0.15

0.09

2.93

1

0.087

1.166

0.978

1.39

VEGF

0.02

0.01

6.49

1

0.011

1.03

1.007

1.053

GREM-1

8.75

2.80

9.77

1

0.002

6357.29

26.222

1541301.23

VEGFC 2578ACC

2.18

1.42

2.35

1

0.125

8.880

0.547

144.12

2.0

Intercept

− 10.42

3.35

9.62

1

0.002

RHI score

− 2.006

0.85

5.54

1

0.019

0.13

0.02

HIF1A

0.12

0.05

5.08

1

0.024

1.13

1.017

VEGF

0.01

0.00

6.96

1

0.008

1.01

1.004

GREM-1

3.56

1.38

6.63

1

0.010

35.17

2.342

VEGFC 2578ACC

− 0.37

0.82

0.20

1

0.653

0.69

0.137