Variables | DFS (n = 50) | NDFS (n = 30) | Controls (n = 30) | p |
---|---|---|---|---|
Age (years) (mean ± SD) | 68,08 ± 9.81 | 66.95 ± 11,92 | 67.05 ± 13,82 | 0.881 |
SBP (mmHg) (mean ± SD) | 130.34 ± 17.52 | 129.37 ± 17.25 | 125.00 ± 12.24 | 0.47 |
DBP (mmHg) (mean ± SD) | 72.22 ± 10.40 | 74.85 ± 14,64 | 74.500 ± 10,85 | 0.59 |
Height (cm) (mean ± SD) | 167.96 ± 15,19 | 169.90 ± 7,71 | 164.20 ± 7,82 | 0.21 |
Weight (kg) (mean ± SD) | 82.98 ± 19.87 | 83.80 ± 22.19 | 72.75 ± 13.16 | 0.95 |
BMI (kg/m2) (mean ± SD) | 28.58 ± 6.32 | 28,98 ± 6.54 | 27.11 ± 5.61 | 0.54 |
RHI (mean ± SD) | 1.42 ± 0.49 | 1.67 ± 0.43 | 2.03 ± 0.66 | < 0.0005 |
MMSE (mean ± SD) | 25.62 ± 3.36 | 26.35 ± 3.53 | 29,00 ± 1.29 | < 0.0005 |
HbA1c (%) (mean ± SD) | 8.07 ± 1.46 | 7.68 ± 2.02 | 5,89 ± 0.57 | 0.32 |
IL-6 (pg/mL) (mean ± SD) | 25.99 ± 52.73 | 5.04 ± 4.92 | 3,09 ± 1.91 | 0.70 |
TNF-alpha (pg/mL)(mean ± SD) | 3,.46 ± 3.08 | 2.97 ± 0.71 | 2.15 ± 0.90 | 0.304 |
VEGF (pg/mL)(mean ± SD) | 191.40 ± 200 | 98,27 ± 56.92 | 71.01 ± 52.59 | 0.022 |
eNOS (ng/mL)(mean ± SD) | 2.47 ± 8.19 | 1.01 ± 1.67 | 1.063 ± 1.19 | 0.606 |
HIF-1alpha (ng/mL)(mean ± SD) | 40.18 ± 10.80 | 33.50 ± 6.16 | 33.85 ± 6.84 | 0.010 |
Gremlin-1 (ng/mL)(mean ± SD) | 1.72 ± 0.512 | 1.31 ± 0.21 | 1.11 ± 0.19 | < 0.0005 |