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Table 2 Results of one-way analysis of variance for diabetes mellitus type 2 patients with and without diabetic foot syndrome and for controls

From: Metabolic memory in diabetic foot syndrome (DFS): MICRO-RNAS, single nucleotide polymorphisms (SNPs) frequency and their relationship with indices of endothelial function and adipo-inflammatory dysfunction

Variables

DFS (n = 50)

NDFS (n = 30)

Controls (n = 30)

p

Age (years) (mean ± SD)

68,08 ± 9.81

66.95 ± 11,92

67.05 ± 13,82

0.881

SBP (mmHg) (mean ± SD)

130.34 ± 17.52

129.37 ± 17.25

125.00 ± 12.24

0.47

DBP (mmHg) (mean ± SD)

72.22 ± 10.40

74.85 ± 14,64

74.500 ± 10,85

0.59

Height (cm) (mean ± SD)

167.96 ± 15,19

169.90 ± 7,71

164.20 ± 7,82

0.21

Weight (kg) (mean ± SD)

82.98 ± 19.87

83.80 ± 22.19

72.75 ± 13.16

0.95

BMI (kg/m2) (mean ± SD)

28.58 ± 6.32

28,98 ± 6.54

27.11 ± 5.61

0.54

RHI (mean ± SD)

1.42 ± 0.49

1.67 ± 0.43

2.03 ± 0.66

 < 0.0005

MMSE (mean ± SD)

25.62 ± 3.36

26.35 ± 3.53

29,00 ± 1.29

 < 0.0005

HbA1c (%) (mean ± SD)

8.07 ± 1.46

7.68 ± 2.02

5,89 ± 0.57

0.32

IL-6 (pg/mL) (mean ± SD)

25.99 ± 52.73

5.04 ± 4.92

3,09 ± 1.91

0.70

TNF-alpha (pg/mL)(mean ± SD)

3,.46 ± 3.08

2.97 ± 0.71

2.15 ± 0.90

0.304

VEGF (pg/mL)(mean ± SD)

191.40 ± 200

98,27 ± 56.92

71.01 ± 52.59

0.022

eNOS (ng/mL)(mean ± SD)

2.47 ± 8.19

1.01 ± 1.67

1.063 ± 1.19

0.606

HIF-1alpha (ng/mL)(mean ± SD)

40.18 ± 10.80

33.50 ± 6.16

33.85 ± 6.84

0.010

Gremlin-1 (ng/mL)(mean ± SD)

1.72 ± 0.512

1.31 ± 0.21

1.11 ± 0.19

 < 0.0005

  1. SBP: systolic blood pressure; DBP: diastolic blood pressure; BMI: body mass index; RHI: reactive hyperaemia index; MMSE: mini-mental state examination; HbA1c: glycated haemoglobin; TNF-alfa: tumor necrosis factor-alfa; VEGF: Vascular Endothelial Growth Factor; NOS: endothelial Nitric-Oxid Synthase; HIF-1 alfa: Hypoxia-inducible factor 1-alpha