Table 1 Demographic and clinical variables in Diabetes Mellitus type 2 patients with and without Diabetic Foot Syndrome and in healthy controls

Sex M/F

37/13

27/13

12/8

0.524

Hypertension (n/%)

38/76

29/70

8/40

0.014

Cardiovascular events (n/%)

18/36

12/22

4/20

0.407

Stroke (n/%)

5/10

12/22

2/10

0.407

Dyslipidemia (n/%)

36/72

18/38

4/20

 < 0.0005

Smoking (n/%)

24/48

9/23

9/45

0.008

Beta-blockade (n/%)

19/38

16/40

5/25

0.529

Calcium channel blockers (n/%)

14/28

7/18

5/25

0.555

ACE inhibitors or ARB (n/%)

23/46

17/40

3/15

0.052

Statin (n/%)

34/68

19/50

5/25

0.004

Antiplates drugs (n/%)

34/68

14/35

6/30

0.001

GLP-1-ra or a DPP-4 inh (n/%)

5/10

19/48

0/0

0.000

Sulfonylurea (n/%)

2/4

5/13

0/0

0,103

Metformin (n/%)

9/18

22/50

1/5

 < 0.0005

Insulin therapy (n/%)

41/82

13/35

0/0

 < 0.0005