Table 1 Baseline characteristics of the study population

Cumulative characteristics

 CumCRP, mg/L

1.5 (0.8,3.0)

1.3 (0.7,2.4)

1.3 (0.7,2.5)

1.9 (1.0,3.7)

2.2 (1.1,4.3)

 < 0.01

 CumAIP

− 0.06 ± 0.27

− 0.06 ± 0.27

− 0.05 ± 0.29

− 0.07 ± 0.24

− 0.10 ± 0.22

 < 0.01

 CumTG, mmol/L

1.3 (1.0,1.9)

1.4 (1.0,2.0)

1.4 (1.0,2.1)

1.2 (0.9,1.7)

1.1 (0.9,1.5)

 < 0.01

 CumHDL, mmol/L

1.5 (1.3,1.8)

1.5 (1.4,1.7)

1.6 (1.4,1.8)

1.5 (1.3,1.7)

1.4 (1.2,1.7)

 < 0.01

Baseline characteristics

 Age, years

52.1 ± 11.8

33.4 ± 3.8

45.1 ± 2.7

63.5 ± 2.9

74.6 ± 4.1

 < 0.01

 AIP

− 0.06 ± 0.31

− 0.03 ± 0.32

− 0.05 ± 0.33

− 0.09 ± 0.29

− 0.12 ± 0.27

 < 0.01

 Male, no. (%)

32,290 (75.2)

4694 (73.8)

8340 (72.4)

5972 (78.0)

2832 (81.9)

 < 0.01

 BMI, kg/m²

25.0 ± 3.3

24.7 ± 3.8

24.9 ± 3.2

25.4 ± 3.3

24.7 ± 3.4

 < 0.01

 SBP, mmHg

129.4 ± 18.6

119.2 ± 13.7

124.5 ± 15.9

137.4 ± 19.6

141.4 ± 20.6

 < 0.01

 DBP, mmHg

80.7 (79.3,90.0)

80.0 (71.5,85.0)

80.7 (78.7,90.0)

83.3 (80.0,90.7)

80.7 (80.0,90.0)

 < 0.01

 FBG, mmol/L

5.2 ± 0.6

5.1 ± 0.6

5.2 ± 0.6

5.3 ± 0.6

5.3 ± 0.6

 < 0.01

 HDL-C, mmol/L

1.5 (1.3,1.8)

1.4 (1.2,1.8)

1.5 (1.2,1.8)

1.5 (1.3,1.9)

1.5 (1.3,1.9)

 < 0.01

 LDL-C, mmol/L

2.6 ± 0.8

2.5 ± 0.7

2.6 ± 0.7

2.6 ± 0.9

2.6 ± 0.9

 < 0.01

 TC, mmol/L

5.0 ± 1.0

4.7 ± 0.9

4.9 ± 0.9

5.1 ± 1.0

5.1 ± 1.0

 < 0.01

 TG, mmol/L

1.3 (0.9,1.8)

1.3 (0.9,1.9)

1.3 (0.9,2.0)

1.2 (0.9,1.7)

1.1 (0.8,1.6)

 < 0.01

 Creatine, umol/L

79.9 ± 21.1

78.4 ± 20.8

78.5 ± 20.3

81.9 ± 19.3

84.9 ± 21.1

 < 0.01

 HsCRP, mg/L

1.0 (0.5,2.4)

0.8 (0.3,1.9)

0.9 (0.4,2.2)

1.2 (0.7,2.7)

1.4 (0.8,3.2)

 < 0.01

Alcohol consumption, no. (%)

 < 0.01

 No

27,879 (64.9)

3700 (58.1)

6653 (57.7)

9082 (64.8)

5736 (74.9)

2762(79.8)

 Yes

15,046 (35.1)

2664 (41.9)

4868 (42.3)

4895 (35.2)

1922 (25.1)

697 (20.2)

Smoking status, no. (%)

 < 0.01

 Never

26,418 (61.5)

3798 (59.7)

6522 (56.6)

8119 (58.3)

5329 (69.6)

2650 (76.6)

 Former

1943 (4.6)

233 (3.6)

466 (4.0)

650 (4.7)

409 (5.3)

185 (5.3)

 Current

14,564 (33.9)

2333 (36.7)

4533 (39.4)

5154 (37.0)

1920 (25.1)

624 (18.1)

Education, no. (%)

 < 0.01

 Less than high school

32,554 (75.8)

2881 (45.3)

8682 (75.4)

11,843(85.1)

6464 (84.4)

2684 (77.6)

 High school and above

10,371 (24.2)

3483 (54.7)

2839 (24.6)

2080 (14.9)

1194 (15.6)

775 (22.4)

Physical activity, no. (%)

 < 0.01

 Low

14,412 (33.5)

2370 (37.2)

4407 (38.3)

4774 (34.3)

1901 (24.8)

960 (27.8)

 Moderate

22,479 (52.4)

3508 (55.2)

6075 (52.7)

7204 (51.7)

4004 (52.3)

1688 (48.8)

 High

6034 (14.1)

486 (7.6)

1039 (9.0)

1945 (14.0)

1753 (22.9)

811 (23.4)

 Family history of diabetes

2290 (5.3)

561 (8.8)

837 (7.3)

703 (5.0)

162 (2.1)

27 (0.8)

 < 0.01

 Hypertension

20,630 (48.1)

1295 (20.3)

4559 (39.6)

7242 (52.0)

4985 (65.1)

2549 (73.7)

 < 0.01

 Dyslipidemia

11,691 (27.2)

1673 (26.3)

3196 (27.7)

3973 (28.5)

2021 (26.4)

828 (23.9)

 < 0.01

 Antihypertensives, no. (%)

2274 (5.3)

45 (0.7)

290 (2.5)

708 (5.1)

769 (10.0)

462 (13.4)

 < 0.01

 Statin, n (%)

251 (0.6)

16 (0.3)

47 (0.4)

81 (0.6)

70 (0.9)

37 (1.1)

 < 0.01

 Fibrate, n (%)

94 (0.2)

6 (0.1)

23 (0.2)

34 (0.2)

23 (0.3)

8 (0.2)

0.024